天然产物研究与开发 ›› 2015, Vol. 27 ›› Issue (2): 360-366.doi: 10.16333/j.1001-6880.2015.02.032

• 综述 • 上一篇    下一篇

植物源脂肪酶抑制剂研究进展

李强,任虹*,王友升   

  1. 北京工商大学食品学院 北京市食品风味化学重点实验室 食品添加剂与配料北京高校工程研究中心 食品质量与安全北京实验室,北京 100048
  • 出版日期:2015-02-15 发布日期:2015-02-15

Review on Pancreatic Lipase Inhibitors Derived from Plants

LI Qiang,REN Hong*, WANG You-sheng   

  1. Beijing Technology & Business University,Beijing Higher Institution Engineering Research Center of Food Additives and Ingredients,Beijing Key Laboratory of Flavor Chemistry,Beijing Laboratory for Food Quality and Safety,Beijing 100048,China
  • Online:2015-02-15 Published:2015-02-15

摘要: 脂肪酶抑制剂通过抑制脂肪酶的活性,减少食物中脂类物质的消化和吸收,达到控制和治疗肥胖的目的。植物来源的天然产物化合物具有来源广泛、结构多样、特异性高、毒性低等特点,因而从植物中筛选安全有效的脂肪酶抑制剂成为研究热点。本文综述了脂肪酶活性测定方法以及植物来源的不同结构类型的脂肪酶抑制剂研究进展。

关键词: 脂肪酶活性测定, 脂肪酶抑制剂, 植物源化合物

Abstract: Lipase inhibitors can reduce the digestion and absorption of dietary lipids by inhibiting pancreatic lipase activity,achieving the purpose of the control and treatment of obesity.Plantderived natural products have a lot of virtues,such as a wide range of sources,structural diversity,highly specificity and low toxicity.Therefore,screening of safe and effective lipase inhibitors derived from plant become a hot topic.This paper reviewed both the methods of determination of lipase inhibiting activity and the lipase inhibitors derived from plants based on the chemical structure.

Key words: methods of determination of lipase inhibiting activity, pancreatic lipase inhibitor, plant-derived natural products

中图分类号: 

Q814.9