天然产物研究与开发 ›› 2015, Vol. 27 ›› Issue (4): 609-612.doi: 10.16333/j.1001-6880.2015.04.010

• 研究简报 • 上一篇    下一篇

石柑子中酚酸类化学成分研究

纪明昌1,2,郭大乐3,蒋舜媛2*,肖世基3,周燕3,丁立生3   

  1. 1 泸州医学院,泸州 646000;2 四川省中医药科学院;3 中国科学院成都生物研究所,成都 610041
  • 出版日期:2015-04-28 发布日期:2015-05-08

Phenolic Components from Pothos chinensis

JI Ming-chang1,2,GUO Da-le3,JIANG Shun-yuan2*,XIAO Shi-ji3,ZHOU Yan3,DING Li-sheng3   

  1. 1 Luzhou Medical College,Luzhou 646000,China; 2 Sichuan Academy of Traditional Medicine Sciences; 3 Chengdu Institute of Biology,Chinese Academy of Sciences,Chengdu 610041,China
  • Online:2015-04-28 Published:2015-05-08

摘要: 对石柑子全草中的酚酸类化学成分进行研究。应用各种柱色谱及制备液相色谱等分离方法进行分离纯化,根据化合物的理化性质和波谱数据进行结构鉴定。结果从石柑子全草的甲醇提取物中共分离得到19个酚酸类化合物,分别鉴定为:苯甲酸(1)、对甲氧基苯甲酸(2)、对甲基苯甲酸(3)、对羟基苯甲酸(4)、香草酸(5)、丁香酸(6)、3,4,5-三甲氧基肉桂酸(7)、3,4-二甲氧基肉桂酸(8)、阿魏酸(9)、对羟基肉桂酸(10)、对羟基苯甲醛(11)、香兰素(12)、丁香醛(13)、对甲氧基苯丙酸(14)、对羟基苯丙酸(15)、(R)-2-羟基-1-(4-羟基-3-甲氧基苯)-1-丙酮(16)、3-羟基-1-(4-羟基-3-甲氧基苯)-1-丙酮(17)、对羟基苯乙醇(18)、邻苯二甲酸二异丁酯(19)。化合物1~4、6~19均为首次从该属植物中分离得到。

关键词: 石柑子, 石柑属, 化学成分, 酚酸类化合物, 结构鉴定

Abstract: To investigate the chemical constituents of phenolic acids in the whole herbs of Pothos chinensis. The chemical constituents were isolated and purified by various column chromatographic methods and preparative HPLC.Their structures were identified by physicochemical properties and spectral analysis.Nineteen compounds were isolated from the methanol extract and identified as benzoic acid (1),p-anisic acid (2),p-toluic acid (3),p-hydroxybenzoic acid (4),vanillic acid (5),syringic acid (6),3,4,5-trimethoxycinnamic acid (7),3,4-dimethoxycinnamic acid (8),ferulic acid (9),p-hydroxycinnamic acid (10),p-hydroxybenzaldehyde (11),vanillin (12),syringaldehyde (13),p-methoxyphenyl-propionic acid (14),p-hydroxyphenyl-propionic acid (15),(R)-2-hydroxy-1(4-hydroxy-3-methoxypheny)propan-1-one (16),ω-hydro-xypropioguaiacone (17),p-hydroxy phenylethanol (18),diisobutyl phthalate (19).Compounds 1-4 and 6-19 were isolated from the plants in this genus for the first time.

Key words: Pothos chinensis (Raf.) Merr., Pothos L.;chemical constituents;phenolic acids;structural identification

中图分类号: 

R284.2