关键词: 君西, 炮制方法, 微量元素, 肠推进, 胃排空

Abstract: Tibetan medicine "Junxi" is widely used in Tibetan historical preparations.Different types and quantities of supplementary material used in different processing methods lead processed products having different medicinal properties.Through researching on the correlation between the content variation of trace elements after processing and pharmacological function,this study explored the modern pharmacology of "Junxi".Six traditional processing methods of Tibetan medicine "Junxi" were selected in this study,and the contents of Ca,Mg,Fe,Mn,Zn,Cu in samples after processing were determined by atomic absorption spectrometer (Flame method,Graphite furnace method).Finally the effects of processed products on intestinal propulsion and gastric emptying in mice was detected by combining with modified phenol red content determination method.The results showed the contents of trace element Ca,Mg,Fe,Mn,Zn,Cu of traditional "ash" processing were significantly higher than these of other methods,but the elements content showed no regular pattern in the remaining groups.Traditional "ash" processing,"thermal" and "burning" processing groups also had higher promotion rate for gastric emptying and intestinal propulsive than these of other groups.These results indicated Tibetan medicine "Junxi" after "hot" processing had certain positive effect on intestinal propulsion and gastric emptying,but may not necessarily linked with the contents of trace elements.These results gave some hints that the therapeutic effects of "Junxi" may be consistent with the theory of the processing for Bacon's disease in Tibetan traditional medicine.

Key words: Junxi, processing methods, trace element, intestinal propulsion, gastric emptying