天然产物研究与开发 ›› 2016, Vol. 28 ›› Issue (2): 232-235.doi: 10.16333/j.1001-6880.2016.2.011

• 研究简报 • 上一篇    下一篇

显脉獐牙菜化学成分研究Ⅱ

李兆云1,王志远1,肖怀2,李龙星2*   

  1. 1 德宏师范高等专科学校生命科学系,芒市 678400 ;2 大理大学药学与化学学院,大理 671000
  • 出版日期:2016-02-29 发布日期:2016-03-07

Chemical Constituents of Swertia nervosaⅡ

LI Zhao-yun1,WANG Zhi-yuan1,XIAO Huai2,LI Long-xing2*   

  1. 1 Department of Life Sciences,Dehong Teacher′s College,Yunnan Mangshi 678400,China;  2 College of Pharmacy and Chemistry,Dali University,Yunnan Dali 671000,China
  • Online:2016-02-29 Published:2016-03-07

摘要: 对显脉獐牙菜(Swertia nervosa)的化学成分研究。采用系统溶剂提取,常规硅胶柱色谱和薄层色谱进行分离纯化,根据化合物的物理、化学性质,UV、IR、MS、1H NMR、13C NMR等波谱鉴定其结构。从显脉獐牙菜中分离得到10个化合物,分别鉴定为1,5,8-三羟基-3-甲氧基口山酮(1)、1,3,8-三羟基-5-甲氧基口山酮(2)、5,7,3′,4′-四羟基黄酮(3)、3,5,7,3′,4′-四羟基黄酮(4)、2-C-β-D-吡喃葡萄糖-1,3,6,7-四羟基口山酮(5)、獐牙菜苦苷(6)、当药苦酯苷(7)、羟基当药苦酯苷(8)、齐墩果酸(9)、胡萝卜苷(10),化合物3~5、7、8和10为首次从显脉獐牙菜中分离得到。

关键词: 显脉獐芽菜, 化学成分, 黄酮, 口山酮

Abstract: To study the chemical constituents of Swertia nervosa. The constituents were separated and purified by column chromatography with silica gel.Their structures were identified on the basis of spectral analysis such as UV,IR,MS, 1H NMR and 13C NMR.Ten compounds were isolated and identified as 1,5,8-trihydroxy- 3- methoxyxa- nthone (1),1,3,8-trihydroxy-5-methoxyxanthone (2),5,7,3′,4′-tetrahydroxyflavone (3),3,5,7,3′,4′- pentahydroxy flavone (4),2-C-β-Dglucopyranosyl-1,3,6,7-tetrahydroxyxanthone (5),swertamarin (6),amarogentin (7),amaroswerin (8),oleanolic acid (9) and daucosterol (10).compound 35,7,8 and 10 were isolated from S.nervosa for the first time.

Key words: Swertia nervosa, chemical constituents, flavones, xanthones

中图分类号: 

R284.1