天然产物研究与开发 ›› 2017, Vol. 29 ›› Issue (5): 787-790.doi: 10.16333/j.1001-6880.2017.5.011

• 研究简报 • 上一篇    下一篇

平滑苍耳果实化学成分研究

王汝冰,邓仕东,屈晶*,庾石山*   

  1. 中国医学科学院&北京协和医学院药物研究所天然药物活性物质与功能国家重点实验室,北京 100050
  • 出版日期:2017-05-31 发布日期:2017-06-09

Chemical Constituents from Fruits of Xanthium chinense Mill.

WANG Ru-bing,DENG Shi-dong,QU Jing*,YU Shi-shan*   

  1. Institute of MateriaMedica,Chinese Academy of Medical Sciences and Perking Union Medical College, State laboratory of bioactive substance and function of natural medicines,Beijing 100050,China
  • Online:2017-05-31 Published:2017-06-09

摘要: 利用各种色谱技术,从平滑苍耳干燥果实95%乙醇提取物中分离得到9个化合物。运用质谱、核磁等波谱学技术鉴定了它们的结构,分别为二氢苍耳烯吡喃(dihydro-xanthienopyran,1)、苍耳烯吡喃(xanthienopyran,2)、地芰普内脂(loliolide,3)、3-isopropyl-5-acetoxycycl-ohexene-2-one-1(4)、(E)-2,5-dihydroxycinnamic acid(5)、咖啡酸(caffeic acid,6)、咖啡酸乙酯(caffeic acid ethyl ester,7)、绿原酸(chlorogenic acid,8)、甲氧基寿菊素(axillarin,9)。其中化合物1为新化合物,化合物2~9均为首次从该植物中分离得到。

关键词: 平滑苍耳, 菊科, 二氢苍耳烯吡喃

Abstract: Ninecompounds were isolated from Xanthiumchinense. By means of ESI-MS and NMR,their structures were identified as dihydro-xanthienopyran(1),xanthienopyran(2),oliolide(3),3-isopropyl-5-acetoxycyclohexene-2-one-1(4),(E)-2,5-dihydroxycinna mic acid(5),caffeic acid(6),caffeic acid ethyl ester(7),chlorogenic acid(8),axillarin(9). Among 1~9,1 was obtained as a new compounds,while 2~9 were first isolated from X. chinense.

Key words: Xanthiumchinense Mill., Compositae, dihydro-xanthienopyran