天然产物研究与开发 ›› 2018, Vol. 30 ›› Issue (11): 2000-2008.doi: 10.16333/j.1001-6880.2018.11.024

• 综述 • 上一篇    下一篇

延胡索化学成分及药理活性研究进展

冯自立1*,赵正栋1,刘建欣2   

  1. 1陕西理工大学生物科学与工程学院;2汉中市植物提取产业研发中心,汉中 723000
  • 出版日期:2018-12-03 发布日期:2018-12-03
  • 基金资助:

    陕西省科技厅重点科技项目(2016ZY-FP-01-05);陕西理工大学博士启动基金(SLGQD2017-11)

Research Progress on Chemical Components and Pharmacological Effects of Corydalis yanhusuo

FENG Zi-li1*,ZHAO Zheng-dong1,LIU Jian-xin2   

  1. 1College of Biological Science & Engineering,Shannxi University of Technology; 2Plant extract industry research and Development Center of Hanzhong,Hanzhong 723000,China
  • Online:2018-12-03 Published:2018-12-03

摘要: 延胡索的化学成分及药理活性经过持续研究取得了系统的成果。本文以化学结构分类为线索重点对原小檗碱类、阿朴菲类、原阿片类、异喹啉类等69个生物碱和甾体、有机酸、黏液质、氨基酸和挥发油27个已确认结构的化合物进行归类整理。结合最新研究文献,阐述了延胡索在镇痛镇静、心血管系统作用、消化系统作用、抗肿瘤、抗炎领域的药理活性研究进展,以期为药材的进一步开发提供参考。

关键词: 延胡索, 化学成分, 药理活性

Abstract: The continuing researches on chemical components and pharmacological effects of Corydalis yanhusuo have been obtained systematic results in recent decades.69 alkaloids of original berberines,aporphines,original opioids,isoquinolines,and 26 compounds listed structures of steroids,organic acids,phlegmatics,amino acids and volatile oils have been classified and arranged with chemical structure classification as key basis.Together with the latest research literatures,this review summarized the research progress on pharmacological effects of Corydalis yanhusuo in sedation,analgesia,cardiovascular system,digestive system,antitumor,anti-inflammatory,in order to provide reference for further research and development of medicinal materials.

Key words: Corydalis yanhusuo, chemical components, pharmacological effects

中图分类号: 

R284