The 18 inorganic elements of Maodongqing were determinated by inductively coupled plasma mass spectrometry (ICP-MS) (Al,Ti,V,Cr,Mn,Fe,Co,Ni,Zn,Zr,Ba,Sn,Sb,Pb,Cu,Cd,As,Hg),and performed by heat map and cluster analysis.The 18 inorganic elements of Maodongqing from 8 different sources were determined.All samples were digested by microwaves.The Ge,In,and Sc elements were used as the internal standards.The standard substance of Astragalus were took as a quality control standard substance.The linear relationship between the elements were all good.The correlation coefficient (r) were all greater than 0.999 0.The detection limit of the instrument was 0.020~106.6 39 mg/kg.The detection limit of the method was 0.002~10.66 4 mg/kg.The recoveries were all in the range of 82.4%~110.8% which with RSD of 1.2%~11.7%.And the content of Mn,Fe,Zn and Ba elements in the 8 batches of Maodongqing were higher,the content of Sb,Sn,Zr,As and Hg elements were lower.The results from cluster analysis showed that there were significant regional differences in the content of 18 inorganic elements in Maodongqing.The method can be used for the quality control of inorganic elements in Maodongqing.This article provides some help to investigate the effectiveness and safety of Maodongqing.