天然产物研究与开发 ›› 2024, Vol. 36 ›› Issue (11): 1972-1997.doi: 10.16333/j.1001-6880.2024.11.017 cstr: 32307.14.1001-6880.2024.11.017

• 综述 • 上一篇    

鹰爪花属植物化学成分和生物活性的研究进展

赵   培1,2,3,刘水林2,陈   银2,黄胜雄2*   

  1. 1银川市中医医院,银川 750001;2中国科学院昆明植物研究所 植物化学与西部植物资源持续利用国家重点实验室,昆明 650201;3成都中医药大学民族医药学院,成都 611137
  • 出版日期:2024-11-25 发布日期:2024-11-25
  • 基金资助:
    2022年银川市学术技术带头人储备工程项目(2022-37);国家杰出青年科学基金(8222500537)

Research progress on chemical constituents and biological activities of Artabotrys plants

ZHAO Pei1,2,3,LIU Shui-lin2,CHEN Yin2,HUANG Sheng-xiong2*   

  1. 1Yinchuan Hospital of Traditional Chinese Medicine,Yinchuan 750001,China;2State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,China;3School of Ethnic Medicine,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China
  • Online:2024-11-25 Published:2024-11-25

摘要: 鹰爪属植物在全球范围内现存100多种,在我国有4种,主要分布在南部,有悠久的药用历史,主要用于疟疾、风湿等顽疾。经现代药化学和药理学研究证实该属植物的化学成分种类多样,涉及十几个分类,主要有生物碱类、萜类、甾体类、环己烯类、黄酮类、醌类、苯丙素类及挥发油等,生物活性也十分丰富,具有抗肿瘤、抗菌、抗病毒、抗疟、抗虫、抗生育、抗凝血、抗血小板、抗氧化和细胞保护作用等。本文对其化学成分和生物活性进行详细综述,为其资源开发研究奠定了理论基础。

关键词: 鹰爪属, 阿朴菲, 倍半萜, 物质基础, 生物活性

Abstract:

There are more than 100 kinds of Artabotrys plants extant in the world.There are four species in China,which are mainly distributed in the south and people have a long medicinal history,mainly using it for malaria,rheumatism and other stubborn diseases.Modern pharmacochemical and pharmacological studies have confirmed that the chemical constituents of Artabotrys plants are diversified,involving more than a dozen categories,including alkaloids,terpenoids,cyclohexenes,steroids,flavonoids,quinones,phenylpropanes and volatile oils,etc.The biological activities of this genus are also very rich,with anti-tumor,antibacterial,antiviral,antimalarial,anti-insect,antifertility,antithrombin,antiplatelet,antioxidative,cytoprotection and so on.In this paper,the chemical constituents and biological activities of the plant were reviewed in detail,which laid a theoretical foundation for its resource development.

Key words: Artabotrys, aporphines, sesquiterpenoids, material basis, biological activity

中图分类号:  R932