天然产物研究与开发 ›› 2024, Vol. 36 ›› Issue (5): 900-917.doi: 10.16333/j.1001-6880.2024.5.018

• 综述 • 上一篇    

杜仲叶化学成分、药理活性及现代应用研究进展

李婉玉1,2,张家旭2,3,谢兴文1* ,石晓峰2*   

  1. 1甘肃中医药大学附属医院,兰州 730000;2甘肃省医学科学研究院,兰州 730050;3甘肃中医药大学,兰州730000
  • 出版日期:2024-05-28 发布日期:2024-05-29
  • 基金资助:
    甘肃省科技重大专项(22ZD6FA021-4)

Research progress on chemical components,pharmacological activities,and modern applications of Eucommiae Folium

LI Wan-yu1,2,ZHANG Jia-xu2,3,XIE Xing-wen1*,SHI Xiao-feng2*   

  1. 1Affiliated Hospital of Gansu University of Chinese Medicine,Lanzhou 730000,China;2Gansu Academy of Medical Science,Lanzhou 730050,China;3Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China
  • Online:2024-05-28 Published:2024-05-29

摘要:

杜仲叶是一种传统中药,现收录于《中华人民共和国药典》一部,同时其作为一种药食两用中药,具有较高的研究价值和开发潜力。现代研究表明,杜仲叶主要含有黄酮类、酚酸类、木脂素类、环烯醚萜类等化学成分,具有抗氧化、降血压、降血脂、神经保护和骨保护等药理作用。目前已研制和开发出较多以杜仲叶为主药或原料的药品、保健品和食品,在医疗、化工和养殖业等多个领域均有应用。该文通过检索近20年国内外对杜仲叶的相关研究报道,对其化学成分、药理活性和应用进行整理总结,为后续杜仲叶的研究及资源开发提供科学依据。

关键词: 杜仲叶, 化学成分, 药理活性, 开发利用

Abstract:

Eucommiae Folium is a traditional Chinese medicine included in the Chinese Pharmacopoeia and valued for their potential as a medicinal and edible herb.Modern research has shown that Eucommiae Folium contains various chemical components,including flavonoids,phenolic acids,lignans,and iridoids,which exhibit pharmacological activities such as antioxidation,blood pressure reduction,lipid-lowering,neuroprotection,and bone protection.At present,a large number of drugs,health products,and foods have been developed with Eucommiae Folium as the main drug or raw material,and have been applied in various fields such as medical treatment,chemical industry,and animal husbandry.This review summarizes the chemical components,pharmacological activities,and applications of Eucommiae Folium based on literature searches of domestic and foreign studies over the past 20 years,providing scientific evidence for future research and resource development.

Key words: Eucommiae Folium, chemical composition, pharmacological activity, development and utilization

中图分类号:  R932