天然产物研究与开发 ›› 2025, Vol. 37 ›› Issue (2): 361-374.doi: 10.16333/j.1001-6880.2025.2.018 cstr: 32307.14.1001-6880.2025.2.018

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蓍属植物的化学成分及药理活性研究进展

王真真,马晓莉,南泽东,江志波*   

  1. 北方民族大学化学与化学工程学院 国家民委化工技术基础重点实验室,银川 750021

  • 出版日期:2025-02-28 发布日期:2025-02-28
  • 基金资助:

    北方民族大学科研启动项目(2021KYQD35);北方民族大学研究生创新项目(YCX23174);宁夏重点研发计划引才专项(2021BEB04019);国家自然科学基金地区项目(82160672)

Research progress on the chemical constituents and pharmacological activities of Achillea L.

WANG Zhen-zhen,MA Xiao-li,NAN Ze-dong,JIANG Zhi-bo*   

  1. Key Laboratory of Chemical Engineering and Technology of State Ethnic Affairs Commission, School of Chemistry and Chemical Engineering,North Minzu University,Yinchuan 750021,China
  • Online:2025-02-28 Published:2025-02-28

摘要:

全球蓍属(Achillea L.)植物约有200多种,广泛分布于北温带。其中多数物种作为民间用药具有上千年历史,且这类植物因具有丰富多样的药用价值和观赏价值而备受关注。研究证据表明蓍属类植物在抗肿瘤、抗菌消炎、抗糖尿病、抗溃疡、抗氧化、抗虫、抗焦虑、抗黑变、抗高血压、抗哮喘、抗生精、镇痛解痉、愈伤等方面均表现出显著的药理活性。本文对2004年以来蓍属植物的化学成分及其药理活性研究进行系统的总结,为蓍属类植物药理活性物质进一步挖掘及该属药材综合开发利用提供参考。

关键词: 蓍属, 萜类, 木脂素, 抗肿瘤, 抗菌消炎

Abstract:

There are more than 200 species of Achillea L.plants worldwide,which are widely distributed in the North temperate zone.Most of these species have been used as folk medicines for thousands of years,and these plants have attracted much attention for their rich and varied medicinal and ornamental values.Studies have shown that Achillea L.has significant pharmacological activities in anti-tumor,antibacterial and anti-inflammatory,anti-diabetes,anti-ulcer,anti-oxidation,anti-insect,anti-anxiety,anti-melanosis,anti-hypertension,anti-asthma,anti-spermatogenesis,analgesic and spasmolysis,callus and other aspects.In this paper,the studies on chemical constituents and pharmacological activities of Achillea L.plants since 2004 are summarized,which can be used as reference for the further exploitation and utilization of Achillea L.

Key words: Achillea L., terpenoids, lignin, antitumor, antibacterial and anti-inflammatory

中图分类号:  R284 R285