天然产物研究与开发 ›› 2025, Vol. 37 ›› Issue (3): 566-575.doi: 10.16333/j.1001-6880.2025.3.020 cstr: 32307.14.1001-6880.2025.3.020

• 综述 • 上一篇    下一篇

精油香薰法的助眠作用及机制研究进展

周露露1，胡  静2，王金林3*，谢建华1*   

  1. 1南开大学元素有机化学研究所，天津 300071；2上海应用技术大学香料香精化妆品学部，上海 201418；3宁波旷世智源工艺设计有限公司，宁波 315012
  • 出版日期:2025-04-01 发布日期:2025-04-01
  • 基金资助:
    国家自然科学基金（92056105，92256303）

Research progress on the effect and mechanism of essential oils inhalation in sleep improvement

ZHOU Lu-lu1, HU Jing2, WANG Jin-lin3 *, XIE Jian-hua1*   

  1. 1State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China; 2School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 201418, China; 3 Ningbo Kwung's Wisdom Art & Design Co., Ltd., Ningbo 315012, China
  • Online:2025-04-01 Published:2025-04-01

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3

摘要：

随着现代生活节奏的加快，失眠已成为困扰多数人的健康难题，其患者群体规模持续扩大。相较于传统镇静类药物可能带来的副作用与依赖性问题，精油香薰法作为一种自然疗法，凭借其安全性高、无显著副作用及使用简便等优势，受到了广泛关注。本文主要综述了多种生物评价模型和临床试验指标，用于评估精油香薰法对睡眠的改善作用，并根据精油的不同香型特征，进一步阐述了如玫瑰、薰衣草等花香系列、柑橘和佛手柑等柑橘调、沉香和檀香等木质调，以及川芎、紫苏等药草香韵精油的助眠效果及其作用机理，以期为精油在助眠领域的应用提供坚实的科学依据。

关键词: 精油, 香薰, 助眠, 机理, 评价模型

Abstract:

 Insomnia has become a significant health issue troubling many people, and the number of sufferers continues to rise each year due to the accelerated pace of modern life. Unlike traditional sedative medications, which may come with side effects and dependency issues, aromatherapy based on essential oils inhalation has garnered widespread attention for its safety, minimal side effects, and ease of use. Hence, various biological evaluation models and clinical trial indicator were firstly reviewed to evaluate the effect of essential oils inhalation on sleep improvement. Additionally, according to different aroma characteristics of essential oils, the sleep-enhancing effects and action mechanisms of essential oils, including floral scents like rose and lavender, citrus scents like orange and bergamot, woody scents like agarwood and sandalwood, and herbal scents like Rhizoma Chuanxiong and perilla, were further summarized. In total, the aim of this paper is to provide a solid scientific basis for the application of essential oils inhalation in sleep improvement.

Key words: essential oils, inhalation, sleep improvement, action mechanism, evaluation models

中图分类号:  TQ654.2

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