天然产物研究与开发 ›› 2010, Vol. 23 ›› Issue (6): 1001-1002.

• 研究简报 • 上一篇    下一篇

耐辐射奇球菌代谢产物中的化学成分

陈 立*,周义龙,郭 晖,李 彬,田 瑛,汪 琼,董俊兴   

  1. 军事医学科学院放射与辐射医学研究所,北京 100850
  • 收稿日期:2009-10-20 出版日期:2011-01-10 发布日期:2011-10-19
  • 通讯作者: chenli7274@yahoo.com.cn
  • 基金资助:

    国家自然科学基金 (30600781)

Chemical Constituents from Metabolites of Deinococcus radiodurans

CHEN Li*,ZHOU Yi-long,GUO Hui,LI Bing,TIAN Ying,WANG Qiong,DONG Jun-xing   

  1. Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850, China
  • Received:2009-10-20 Online:2011-01-10 Published:2011-10-19

摘要:

通过甲醇提取、硅胶柱色谱、重结晶分离纯化,从耐辐射奇球菌(Deinococcus radiodurans)代谢产物中分离得到五个化合物,根据光谱数据鉴定为:腺嘌呤(1),胸腺嘧啶(2),尿嘧啶(3),腺苷(4)和L-丙氨酸(5)。所有成分均为首次从该细菌的代谢产物中得到。

关键词: 耐辐射奇球菌, 代谢产物, 化学成分

Abstract:

Five compounds were isolated from the MeOH extract of Metabolites of Deinococcus radiodurans by silica gel column chromatography and recrystallization. On the basis of spectroscopic data, They were identified as adenine(1), thymine(2), uracil(3), adenosine(4), and L-alanine(5). All compounds were obtained from Metabolites of D. radiodurans for the first time.

Key words: Deinococcus radiodurans, metabolites, chemical constituents