牛耳枫中生物碱的研究

天然产物研究与开发 ›› 2010, Vol. 23 ›› Issue (6): 1024-1027.

牛耳枫中生物碱的研究

朱文粮，罗都强^*，刘召阳

河北大学生命科学学院，药物化学与分子诊断教育部省部共建重点实验室，保定 071002

收稿日期:2009-07-13 出版日期:2011-01-10 发布日期:2011-10-19
通讯作者: duqiangluo@163.com

Alkaloids from Daphniphyllum calycinum Benth.

ZHU Wen-liang, LUO Du-qiang ^*, LIU Zhao-yang

College of Life Science, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding 071002, China

Received:2009-07-13 Online:2011-01-10 Published:2011-10-19
Supported by:
This work was supported by the National Natural Science Foundation of China (30671385), Program for Hundred Excellent Innovation Talents from the Universities and Colleges of Hebei Province and the Key Project of Chinese Ministry of Education.

摘要/Abstract

摘要：

应用各种色谱方法从牛耳枫的茎叶乙醇浸提物中分离得到了8个生物碱，利用波谱（ESI-MS,¹H NMR,¹³C NMR）技术及理化性质分别鉴定为Methyl homosecodaphniphyllate (1)，Daphnezomine M (2)，Caldaphnidine E (3)，Calyciphylline F (4)，Calyciphylline B (5)，Deoxycalyciphylline B (6)，Daphnicyclidin H (7) 和Macropodumine C (8)。

关键词: 牛耳枫, 生物碱, 化学成分

Abstract:

Eight alkaloids were isolated from the stems and leaves of Daphniphyllum calycinum Benth by using various methods of chromatography. On the basis of spectroscopic evidence, their structures were identified as methyl homosecodaphniphyllate(1), daphnezomine M(2), caldaphnidine E(3), calyciphylline F(4), calyciphylline B(5), deoxycalyciphylline B(6), daphnicyclidin H(7), and macropodumine C(8). Compounds 7 and 8 were isolated from this plant for the first time.

Key words: Daphniphyllum calycinum Benth, alkaloids, chemical constituent

朱文粮，罗都强，刘召阳. 牛耳枫中生物碱的研究[J]. 天然产物研究与开发, 2010, 23(6): 1024-1027.

ZHU Wen-Liang, LUO Du-Qiang, LIU Zhao-Yang. Alkaloids from Daphniphyllum calycinum Benth.[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2010, 23(6): 1024-1027.

参考文献

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