β-环糊精包合雨生红球藻皂化产物可行性研究

天然产物研究与开发 ›› 2011, Vol. 23 ›› Issue (4): 700-703.

β-环糊精包合雨生红球藻皂化产物可行性研究

万庆家1*，饶高雄2，王朝军1，张秋玲1，龙祥1

1云南绿A生物工程有限公司，昆明 650106；2云南中医学院，昆明 650500

收稿日期:2010-06-12 出版日期:2011-08-25 发布日期:2011-09-13
基金资助:
科技部科技型中小企业技术创新基金无偿资助项目：新型生物反应器大规模培养红球藻生产虾青素技术研究与开发（09C26215302506）

Feasibility Study on Inclusion Complex of Saponification Product of Haematococcus pluvialis with β-Cyclodextrin

WAN Qing-jia1, RAO Gao-xiong2, WANG Chao-jun1, ZHANG Qiu-ling1, LONG Xiang1

1Yunnan Green A Biological Project Co.,Ltd,Kunming 650106,China; 2Yunnan University of Traditional Chinese Medicine,Kunming 650500,China

Received:2010-06-12 Online:2011-08-25 Published:2011-09-13

摘要/Abstract

摘要： 本文以雨生红球藻皂化产物中虾青素含量为评价指标，对β-环糊精包合雨生红球藻皂化产物可行性进行了实验研究。试验结果表明，当雨生红球藻粉在优选的实验条件下皂化产物经β-环糊精包合后，HPLC检测主要成分组成未见明显变化，包合率可达到90%。于温度40 ℃，湿度75%条件下进行稳定性加速实验，结果表明，经皂化后包合物中虾青素稳定性较好，达到了药物和保健食品原料的稳定性要求，说明该方法可行。

关键词: 雨生红球藻；虾青素；皂化；&beta, -环糊精；包合率；稳定性

Abstract: Feasibility on inclusion complex of saponification product of Haematococcus pluvialis with β-cyclodextrin was studied with astaxanthin content as the quality evaluation criteria. As the results,inclusion rate reached 90% at optimized conditions, and the content of astaxanthin in the saponification of H.pluvialis have no significant change. The stability of astaxanthin reach the requirements as medicine and health food raw materials in the accelerative experiment of stability at 50℃, 75% relative humidity. The results showed that this method is feasible.

Key words: Haematococcus pluvialis, astaxanthin, saponification, β-cyclodextrin, inclusion rate, stability

中图分类号:

O641.4 R943

万庆家，饶高雄，王朝军，张秋玲，龙祥. β-环糊精包合雨生红球藻皂化产物可行性研究[J]. 天然产物研究与开发, 2011, 23(4): 700-703.

WAN Qing-jia, RAO Gao-xiong, WANG Chao-jun, ZHANG Qiu-ling, LONG Xiang. Feasibility Study on Inclusion Complex of Saponification Product of Haematococcus pluvialis with β-Cyclodextrin[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2011, 23(4): 700-703.