黑柄炭角菌的化学成分

天然产物研究与开发 ›› 2011, Vol. 23 ›› Issue (5): 846-849.

黑柄炭角菌的化学成分

杨小龙1*，刘吉开2，罗都强3，张苏1

1河北大学药学院，保定 071002；2中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室，昆明 650204；3河北大学生命科学院药物化学与分子诊断省部共建教育部重点实验室，保定 071002

收稿日期:2009-12-16 出版日期:2011-10-25 发布日期:2011-09-26

Chemical Constituents of Xylaria nigripe

YANG Xiao-long1*, LIU Ji-kai2, LUO Du-qiang3, ZHANG Su1

1College of Pharmaceutical Science, Hebei University, Baoding 071002,China; 2State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China; 3College of Life Science, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding 071002, China

Received:2009-12-16 Online:2011-10-25 Published:2011-09-26

摘要/Abstract

摘要： 从黑柄炭角菌（Xylaria nigripe）子实体中分离得到10个化合物,通过波谱分析等方法分别鉴定为(22E,24R)-麦角甾-5,7,22-三烯-3β-醇（1）、5α,8α-过氧-(22E,24R)-麦角甾- 6,22-二烯-3β-醇（2）、脑苷酯B（3）、脑苷酯 D（4）、stearic acid（5）、甘油的亚油酸三酯（trilinolein, 6）、α-kojibiose（7）、D-阿洛糖醇（8）、L-氨基丙酸（9）和尿囊素（10）。所有化合物均为首次从该子实体中分离得到。

关键词: 黑柄炭角菌, 麦角甾醇, 脑苷酯, 亚油酸三酯

Abstract: Ten known compounds have been isolated from the fruiting bodies of Xylaria nigripe. Their structures were established as (22E,24R)-ergosta-5,7,22-trien-3β-ol (1), 5α,8α-epidiory-(22E,24R)-ergosta-6,22-dien-3β-ol (2), 1-O-β-D-glucopyranosyl- (2S,3R,4E,8E,2′R)-2-N-(2′-hydroxy-palmitoyl)-9-methyl-4,8-sphinga-dienine(3), 1-O-β-D-glucopyranosyl-(2S,3R,4E,8E,2′R)-2-N-(2′-hydroxylocta-decanoyl)-9-methyl-4,8-sphingadienine (4), stearic acid (5), trilinolein (6), α-kojibiose (7), D-allitol (8), L-alanine (9), and allantoin (10) by comprehensive spectroscopic methods. All compounds are reported from this fungus for the first time.

Key words: Xylaria nigripe, sterols, cerebroside, trilinolein

中图分类号:

Q946.91 R284.2

杨小龙，刘吉开，罗都强，张苏. 黑柄炭角菌的化学成分[J]. 天然产物研究与开发, 2011, 23(5): 846-849.

YANG Xiao-long, LIU Ji-kai, LUO Du-qiang, ZHANG Su. Chemical Constituents of Xylaria nigripe[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2011, 23(5): 846-849.

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