天然产物研究与开发 ›› 2014, Vol. 26 ›› Issue (8): 1327-1331.

• 综述 • 上一篇    下一篇

构树新化学成分及生物学活性研究进展

丁 宇1,2,仇 晶1,2,刘小宇1*   

  1. 1 第二军医大学基础部生物化学与分子生物学教研室;2 第二军医大学学员旅十二队,上海 200433
  • 出版日期:2014-08-30 发布日期:2014-11-06

Research Progress on New Chemical Constituents and Biological Activities of Broussonetia papyrifera

DING Yu1,2, QIU Jing1,2, LIU Xiao-yu1*   

  1. 1 Biochemistry and Molecular Biology Department of Basic Medical college,Second Military Medical University; 2 Company 12 of Second Military Medical University,Shanghai 200433 ,China
  • Online:2014-08-30 Published:2014-11-06

摘要: 构树[Broussonetia papyrifera (L.)Vent.]为桑科(Moraceae)构树属(Broussonetia)植物,分布于中国黄河、长江和珠江流域,也见于越南、日本等国家。构树属于传统中药,植物的各部位均可入药,用于治疗疼痛,水肿,痢疾。对构树化学成分的研究从构树的叶、根和果实中发现了黄酮类、木脂素类及萜类等多种化学成分,其中部分成分具有抗菌、抗氧化、细胞毒及抗炎等活性。现对2000年以来从构树中获得的新化合物及其生物学活性研究成果进行总结,为其进一步研究提供参考。

关键词: 构树, 新化合物, 生物学活性

Abstract: Broussonetia papyrifera, one genus of Moraceae, distributes widely in Yellow River,Yangtze River and the Pearl River basins of China.It also can be found in Japan,Vietnam and some other countries. B.papyrifera is one kind of traditional Chinese medicine,and is used to cure pain,edema and dysentery in Chinese traditional therapy.In recent years,there are many new chemical constituents isolated from the leaves,root and fruits of B.papyrifera,identified as flavones,lignans and terpenes.Some of them were reported to have several bioactivities including antioxidation,antimicrobe,anti-inflammatory,cytotoxicity,etc.This paper reviewed the new chemical compounds identified from B.papyrifera and their bioactivities since 2000.

Key words: Broussonetia papyrifera, new chemical compounds, bioactivities

中图分类号: 

R284.2