天然产物研究与开发 ›› 2015, Vol. 27 ›› Issue (Suppl): 10-13.doi: 10.16333/j.1001-6880.2015.S.003

• 研究论文 • 上一篇    下一篇

猴耳环化学成分研究

刘主洁,王欢,祝晨蔯,林朝展*   

  1. 广州中医药大学临床药理研究所,广州 510405
  • 出版日期:2015-12-01 发布日期:2016-01-12

Chemical Constituents of Pithecellobium clypearia Benth.

LIU Zhu-jie,WANG Huan,ZHU Chen-chen,LIN Chao-zhan*   

  1. Institute of Clinical Pharmacology,Guangzhou University of Chinese Medicine,Guangzhou 510405,China
  • Online:2015-12-01 Published:2016-01-12

摘要: 采用正反相硅胶和Sephadex LH-20等柱色谱方法,结合重结晶法对猴耳环提取物进行分离纯化,综合运用光谱、质谱及核磁共振等技术鉴定了11个化合物,分别为:没食子酸(1)、没食子酸乙酯(2)、对羟基苯甲酸(3)、山奈酚-3-O-α-L-吡喃鼠李糖苷(4)、槲皮素-3-O-α-L-吡喃鼠李糖苷(5)、槲皮素(6)、5,3′,4′,5′-四羟基黄烷-7-没食子酸酯(7)、芦丁(8)、木犀草素(9)、杨梅素-3-O-α-L-吡喃鼠李糖苷(10)、木犀草素-7-O-β-D-吡喃葡萄糖苷(11)。其中化合物4、8为首次在猴耳环中报道。

关键词: 猴耳环, 化学成分, 黄酮, 有机酸

Abstract: The chemical constituents of Pithecellobium clypearia Benth.were isolated and purified by chromatographic methods over Sephadex LH-20 and silica gel column, and structures of eleven compounds were elucidated by spectral analysis,including UV,IR,MS, 1H NMR, 13C NMR.There were galliic acid (1),ethyl gallate (2), p-hydroxybenzoie acid (3), kaempferol-3-O-α-L-rhamnopyranoside (4),quercetin-3-O-α-L-rhamnopyranoside (5),quercetin (6),5,3′,4′,5′-tetrahydroxyflavan-7-gallate (7),rutin (8),luteolin (9),myricetin-3-O-α-L-rhamnopyranoside (10),luteolin-7-O-β-D-glucopyranoside (11),respectively.Moreover,compounds 4 and 8 were reported for the first time from P.clypearia.

Key words: Pithecellobium clypearia Benth., chemical constituents, flavonoids, organic acids

中图分类号: 

R284.1