天然产物研究与开发 ›› 2015, Vol. 27 ›› Issue (Suppl): 172-175.doi: 10.16333/j.1001-6880.2015.S.040

• 开发研究 • 上一篇    下一篇

黄连片炮制工艺的研究

胡荣1,冉继春1,瞿显友1,赵燕2,杨荣平1*   

  1. 1 重庆市中药研究院中药资源学(重庆)重点实验室,重庆 400065;2 重庆康迪药业有限公司, 重庆 402660
  • 出版日期:2015-12-01 发布日期:2016-01-12

Preparation Procedure of Rhizoma coptidis Pieces

HU Rong1,RAN Ji-chun1,QU Xian-you1,ZHAO Yan2,YANG Rong-ping1*   

  1. 1 Chongqing Academy of Chinese Materia Medica,Key Laboratory of Chinese materia medica resources (Chongqing),Chongqing 400065,China; 2 Chongqing Kangdi Medicine Industry Co.,Ltd,Chongqing 402660,China
  • Online:2015-12-01 Published:2016-01-12

摘要: 针对目前黄连片炮制方法和过程不规范而导致的黄连片品质差异性较大的问题,本文进行了黄连片炮制关键性步骤“水洗、浸润和干燥”的研究,采用单因素与正交试验法,以黄连总生物碱为评价指标,筛选出了最佳炮制工艺条件:加入2倍量水,水洗1次,150 s,润60 s(在125 ℃和压力0.10 MPa条件下),切薄片,60 ℃干燥3.0 h。由该工艺制备的黄连片总生物碱含量为11.03%。实验结果表明,该黄连片炮制工艺合理、稳定、可行、高效。

关键词: 黄连片, 炮制工艺, 生物碱

Abstract: In order to improve the quality of Rhizoma coptidis pieces resulted by irregular processing method,procedure the influences of washing,infiltrating and drying were investigated to optimize the preparing procedures of R.coptidis pieces.Using single factor experiments and orthogonal test method with total alkaloids as evaluation index,the optimal preparation method of R.coptidis pieces was determined as follows:adding 2 times of water,washing once for 150 s,embellishing 60 s (under the condition of 125 ℃ and 0.10 MPa),sliceling and drying at 60 ℃ for 3.0 h.The preparing procedure is effective,stable and reliable.

Key words: Rhizoma coptidis pieces, preparation procedures, alkaloids

中图分类号: 

R284.2