天然产物研究与开发 ›› 2016, Vol. 28 ›› Issue (增刊2): 341-348.doi: 10.16333/j.10016880.2016.S.036

• 综述 • 上一篇    下一篇

促卵泡生长素相关细胞信号通路的研究进展

胡建文,华荣茂,张仙,刘兰兰,陈飞,曾斌*   

  1. 江西科技师范大学 江西省生物加工过程重点实验室,南昌 330013
  • 出版日期:2016-12-31 发布日期:2017-03-03

The Research Progress of Folliclestimulating Hormone Involved in Cell Signaling Pathway

HU JIANwen,HUA RONGmao,ZHANG Xian,LIU Lanlan,CHEN Fei,ZENG Bin*   

  1. Jiangxi Province Key Laboratory of Bioprocess Engineering,Jiangxi Science & Technology Normal University,Nanchang 330013,China
  • Online:2016-12-31 Published:2017-03-03

摘要: 促卵泡激素(folliclestimulating hormone,FSH)是哺乳动物体内一种具有促进雌性动物子宫内膜生长,卵泡颗粒细胞的增殖与分化,刺激多卵泡发育,合成雌激素等多种生物学功能的糖基化蛋白质激素。我们主要从FSH、促卵泡激素受体(FSHR)分子结构和生物学功能出发综述FSH依赖于G蛋白介导的细胞信号通路和独立于G蛋白有关的细胞信号通路。

关键词: 促卵泡激素, 促卵泡激素受体, 生物学功能, 细胞信号通路

Abstract: Folliclestimulating hormone(FSH)is a kind of important glycoprotein hormones in mammals.It can promote the growth of female animals endometrial and cell proliferation and differentiation of ovarian follicles granulosa,stimulate multiple follicle development,synthetic estrogen,and other biological functions.In this article,we mainly focus on the molecular structure and biological function of FSH and follicle stimulating hormone receptor (FSHR),to review cell signaling pathways involved in G proteindependent and G proteinindependent.

Key words: folliclestimulating hormone, folliclestimulating hormone receptor, biological function, cell signaling pathway

中图分类号: 

Q571