天然产物研究与开发 ›› 2018, Vol. 30 ›› Issue (8): 1376-1381.doi: 10.16333/j.1001-6880.2018.8.015

• 研究简报 • 上一篇    下一篇

勐腊毛麝香化学成分研究

马永鹏1,2,张红霞1,孙果1,杜芝芝1*   

  1. 1中国科学院昆明植物研究所 资源植物与生物技术重点实验室(云南省野生资源植物研发重点实验室),昆明 650201;2中国科学院大学,北京 100049
  • 出版日期:2018-09-04 发布日期:2018-09-04
  • 基金资助:

    中国科学院植物种质资源创新项目(ZSZC-012)

Chemical Constituents from Adenosma buchneroides

MA Yong-peng1,2,ZHANG Hong-xia1,SUN Guo1,DU Zhi-zhi1*   

  1. 1Key Laboratory of Economic Plants and Biotechnology (Yunnan Key Laboratory for Wild Plant Resources), Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,China; 2University of Chinese Academy of Sciences,Beijing 100049,China
  • Online:2018-09-04 Published:2018-09-04

摘要: 综合运用大孔树脂D101、硅胶、葡聚糖凝胶 LH-20柱层析以及半制备型高效液相等色谱方法对勐腊毛麝香(Adenosma buchneroides Bonati)的全株进行了化学成分分离纯化。从该植物的甲醇及甲醇-水提取物中分离得到16个化合物,运用现代波谱技术分别鉴定为:乙酰地黄苷C(1)、1,3,5-三甲氧基苯(2)、对羟基苯甲酸甲酯(3)、对羟基苯甲醛(4)、对甲氧基苄醇(5)、松柏醛(6)、芥子醛(7)、吲哚-3-甲醛(8)、吲哚-3-甲酸(9)、丁香酚-β-D-葡萄糖苷(10)、丁香树脂醇-4-O-β-D-葡萄糖苷(11)、香芹酚-β-D-葡萄糖苷(12)、menthiafolic acid(13)、(8R)-evofolin B(14)、芹菜素(15)、4,4′-二羟基二苄基醚(16)。其中化合物1为新化合物,且化合物1~16均为首次从毛麝香属植物中分离得到。

关键词: 勐腊毛麝香, 化学成分, 苯丙素, 酚酸

Abstract: To investigate the chemical compositions of Adenosma buchneroides,the methanol and aqueous methanol extracts were obtained from its whole plant.The combined extracts were isolated and purified using D101 macroporous resin,silica gel,Sephadex LH-20 column chromatography and semi-preparative HPLC.One new and sixteen known compounds were obtained and their structures were identified,on the basis of modern spectroscopic data and literature data,as acetylmartynoside C (1),1,3,5-trimethoxybenzene (2),p-hydroxybenzoic acid methyl ester (3),p-hydroxybenzaldehyde (4),p-methoxybenzyl alcohol (5),coniferaldehyde (6),sinapaldehyde (7),indole-3-carboxaldehyde (8),indole-3-carboxylic acid (9),eugenol-β-D-glucopyranoside (10),syringaresinol-4-O-β-D-glucopyranoside (11),carvacrol-β-D-glucopyranoside (12),menthiafolic acid (13),(8R)-evofolin B (14),apigenin (15),4,4′-dihydroxydibenzyl ether (16),respectively.All of these compounds were isolated and identified from the genus Adenosma for the first time.

Key words: Adenosma buchneroides, chemical constituents, phenylpropanoids, phenolic acids

中图分类号: 

TQ284.2