天然产物研究与开发 ›› 2018, Vol. 30 ›› Issue (增刊2): 132-137.

• 研究简报 • 上一篇    下一篇

川续断属药用植物6种化学成分含量比较及聚类分析

陈大霞1,2,3,4,谭均1,2,3,张雪1,2,3,潘媛1,2,3,李隆云1,2,3*,张泽4   

  1. 1重庆市中药研究院;2重庆市中药良种选育与评价工程技术研究中心;3中国中医科学院中药资源中心重庆分中心,重庆 400065;4重庆大学生命科学学院,重庆 400044
  • 出版日期:2019-01-18 发布日期:2019-01-18
  • 基金资助:

    现代农业产业技术体系建设专项(CARS-21);重庆市中药材产业技术体系建设项目(2018[5]号);重庆市“科技平台与基地建设”项目(cstc2014ptyjd10001);国家科技部科技人员服务企业行动项目(2009GJF10045);国家“十一五”科技支撑计划(2006BAI06A11-09)

Compare and Cluster Analysis of Six Chemical Constituents in Dipsacus Medicinal Plants

CHEN Da-xia1,2,3,4,TAN Jun1,2,3,ZHANG Xue1,2,3,PAN Yuan1,2,3,LI Long-yun1,2,3*,ZHANG Ze4    

  1. 1Chongqing Academy of Chinese Materia Medica; 2Chongqing Engineering Research Center for Fine Variety Breeding Techniques of Chinese Materia Medica; 3Chongqing Sub-center of National Resource,Center for Chinese Materia Medica,China Academy of Chinese Medical Science,Chongqing 400065,China; 4College of Life Sciences,Chongqing University,Chongqing 400044,China
  • Online:2019-01-18 Published:2019-01-18

摘要: 为评价川续断属8 种药用植物的药用价值,采用高效液相色谱法测定川续断属8 种药用植物干燥根中6种化学成分的含量,并对6 种化学成分进行相关性分析、主成分分析及聚类分析。结果表明:6 种成分平均含量由高到低依次为川续断皂苷VI﹥当药苷﹥绿原酸﹥马钱苷﹥胡萝卜苷﹥β-谷甾醇;在8 种川续断属植物中川续断皂苷VI的含量变化幅度较大,其次是当药苷、马钱苷,其余的3种成分差异不大;显著相关的化学成分为当药苷与马钱苷;极显著相关的有川续断皂苷VI与当药苷、胡萝卜苷与β-谷甾醇、胡萝卜苷与绿原酸及β-谷甾醇与绿原酸;川续断和多裂续断的主成分分值较高,其次为康定续断和大头续断,其余4 种较低;基于6 种化学成分的聚类结果与传统分类相似度并不高。

关键词: 川续断属, 化学成分, 含量变化, 聚类分析

Abstract: To evaluate the value of eight Dipsacus medicinal plants,we determinated 6 chemical constituents in their dry roots by high performance liquid chromatography and carried correlation analysis,principal component analysis and cluster analysis.The results showed that the average content of six medicinal components from high to low were asperosaponin VI,chiratin,chlorogenic acid,loganin,daucosterol,β-sitosterol.The content of asperosaponin VI was changed greatly,followed by chiratin and loganin,but the rest of three components had little difference.Loganin and chiratin were significantly correlated.Asperosaponin VI and sweroside,daucosterol and β-sitosterol,daucosterol and chlorogenic acid,β-sitosterol and chlorogenic acid were extremely significantly correlated.The principal component scores of D.asperoides and D.daliensis var multifidus were higher,followed by D.kangdingensis and D.chinensis,the rest of four species were lower.Based on six chemical compositions,the clustering result is not high compared with the traditional classification.

Key words: Dipsacus, chemical constituents, changes of chemical constituents, cluster analysis

中图分类号:  R931.6