关键词: 马鞭草科, 广东紫珠, 苯丙素类化合物, 抑菌

Abstract: Ten phenylpropanoid compounds were isolated and purified from ethanol extract of Callicarpa kwangtungensis by several chromatographys.Based on spectral analysis and the comparion of literatures,these compounds were identified as 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxy-1-(E)-propenyl)-2,6-dimethoxyphenoxy]-propyl-β-D-glucopyranoside (1)、peiioside A (2)、syringalide A 3'-α-L-rhanmnopyranoside (3)、parvifloroside A (4)、 leucosceptoside B (5)、alyssonoside (6)、longissimoside B (7)、acteoside (8)、forsythoside B (9) and poliumoside (10).Compound 1 was firstly isolated from the plants of Verbenaceae,and compound 4 was firstly isolated from the plants of Callicarpa genus,while compounds 2,5 and 7 were obtained from this plant for the first time.The bacteriostatic activity results showed that four phenylpropanoids (compound 6,8,9 and 10) widespread in C. kwangtungensis had inhibitory activity against S. aureus,E. coliand  P. aeruginosa to some extent.This study provided the experimental basis for the clinical application of C. kwangtungensis in antibacterial fields.

Key words: verbenaceae, Callicarpa kwangtungensis, phenylpropanoid compounds, antibacterial activity