天然产物研究与开发 ›› 2019, Vol. 31 ›› Issue (增刊2): 139-148.doi: 10.16333/j.1001-6880.2019.S.022

• 综述 • 上一篇    下一篇

铁皮石斛化学成分及生物活性研究进展

张帮磊1,3,杨豪男1,3,沈晓静1,2,张冬英1,2,王宣军1,2,盛军1,3*,字成庭1,2*   

  1. 1云南农业大学 普洱茶教育部重点实验室;2云南农业大学理学院;3云南农业大学食品科学技术学院,昆明 650201
  • 出版日期:2019-12-28 发布日期:2019-12-30
  • 基金资助:

    国家自然科学基金(21602196);云南省自然科学基金(2017ZF003,2017FG001(-046),2017FD084);云南农业大学自然科学基金(2015ZR08)

Review on chemical composition and biological activity of Dendrobium candidum

ZHANG Bang-lei1,3,YANG Hao-nan1,3,SHEN Xiao-jing1,2,ZHANG Dong-ying1,2,WANG Xuan-jun1,2,SHENG Jun1,3*,ZI Cheng-ting1,2*   

  1. 1Key Laboratory of Pu-er Tea Science,Ministry of Education,Yunnan Agricultural University;2College of Science,Yunnan Agricultural University;3College of Food Science and Technology,Yunnan Agricultural University,Kunming 650201,China
  • Online:2019-12-28 Published:2019-12-30

摘要: 铁皮石斛为我国传统的名贵中药材,在日常保健和临床治疗中应用广泛,并且受到国内外学者广泛关注。近年来研究表明,铁皮石斛化学成分类别较多,包括多糖、芪类、氨基酸、微量元素、生物碱、挥发油等,其中以多糖及芪类成分为主;药理活性有抗氧化、抗肿瘤、调节免疫力、缓解疲劳、治疗糖尿病等,以抗氧化和抗肿瘤研究为主。本文基于国内外铁皮石斛近20年的文献报道,对其化学成分、分离现状及药理功效相关文献进行整理、分析,系统的综述了其化学成分及药理功效的研究进展,可为今后铁皮石斛资源的深入研究和新药研发提供理论依据。

关键词: 铁皮石斛, 化学成分, 药理作用

Abstract: Dendrobium candidum is a traditional Chinese medicine,widely used in daily health care and clinical treatment,and has been widely concerned by scholars at home and abroad.In recent years,studies have shown that Dendrobium candidum has many chemical components,including polysaccharides, astragalus, amino acids, mineral elements,alkaloids,volatile oils,etc.,of which polysaccharides and astragalus are the main components.Antioxidant,anti-tumor,immune regulation,fatigue relief,treatment of diabetes are the main pharmacological activities,researchers mainly studied on its antioxidant and anti-tumor.Based on the literature reports of Dendrobium candidum  in recent 20 years,the chemical composition,separation status and pharmacological efficacy of Dendrobium candidum  were summarized and analyzed.This paper may provide theoretical basis for further research on Dendrobium candidum resources and new drug research and development in the future.

Key words: Dendrobium candidum, chemical compositions, pharmacological activity

中图分类号: 

R284 R285