天然产物研究与开发 ›› 2022, Vol. 34 ›› Issue (增刊2): 163-168.

• 综述 • 上一篇    下一篇

杨梅素及二氢杨梅素的抗肿瘤研究进展

李   艳,刘   健*   

  1. 蚌埠医学院第一附属医院妇瘤科,蚌埠 233000
  • 出版日期:2022-12-07 发布日期:2022-12-07

Research advances on antitumor effect of myricetin and dihydromyricetin

LI Yan,LIU Jian*   

  1. Department of Gynecologist and Oncology,the First Affiliated Hospital of Bengbu Medical College,Bengbu 233000,China
  • Online:2022-12-07 Published:2022-12-07

摘要: 天然产物具有抗炎、抗氧化、降血糖、调血脂、保肝等多种活性,近来研究表明,天然产物可影响肿瘤细胞行为学变化,如抑制肿瘤细胞增殖、迁移、侵袭等,从而发挥抗肿瘤活性。本文就近年杨梅素及二氢杨梅素的抗肿瘤作用及机制进行总结,一是为后续研究提供研究方向,二是可为临床前期用药提供实验数据支持。

关键词: 杨梅素, 二氢杨梅素, 肿瘤, 分子机制

Abstract:

Natural products have anti-inflammatory,anti-oxidant,hypoglycemic,regulating blood lipid,liver protection and other activities.Recent studies have shown that natural products can affect the behavioral changes of tumor cells,such as inhibiting the proliferation,migration and invasion of tumor cells,thus playing an anti-tumor activity.This paper summarizes the antitumor effect and mechanism of myricetin and dihydromyricetin in recent years,It not only provides ideas and research directions for follow-up research,but also puts forward new ideas for preclinical medication for experimental data support.

Key words: myricetin, dihydromyricetin, tumor, molecular mechanism

中图分类号:  R915