天然产物研究与开发 ›› 2023, Vol. 35 ›› Issue (6): 1081-1087.doi: 10.16333/j.1001-6880.2023.6.017

• 综述 • 上一篇    下一篇

麦角硫因的抗氧化特性及其干预氧化应激相关疾病的研究进展

高青莹，徐建雄*   

  1. 上海交通大学农业与生物学院 上海市兽医生物技术重点实验室，上海 200240
  • 出版日期:2023-06-28 发布日期:2023-06-28
  • 基金资助:
    上海市科技兴农项目（X2019-02-08-00-08-F01155）

Research progress on antioxidative property of ergothioneine and its intervention in oxidative stress-related diseases

GAO Qing-ying,XU Jian-xiong*   

  1. Shanghai Key Laboratory of Veterinary Biotechnology,School of Agriculture and Biology,Shanghai Jiao Tong University,Shanghai 200240,China
  • Online:2023-06-28 Published:2023-06-28

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摘要： 麦角硫因（ergothioneine，ERG）是存在于自然界的一种含硫氨基酸，因其具有较强的清除自由基和抗衰老能力且天然安全无毒，近年来在食品、医药、化妆品等领域广泛应用。麦角硫因作为一种天然高效的抗氧化剂，在与氧化应激相关的疾病预防和治疗中发挥着重要的作用。本文综述了麦角硫因的结构与性质、抗氧化特性，干预氧化应激相关疾病的作用与机制等研究进展，为麦角硫因多元应用提供参考。

关键词: 麦角硫因, 结构, 抗氧化性, 氧化应激, 应用

Abstract:

Ergothioneine (ERG) is a kind of sulfur-containing amino acid existing in nature.It has been widely used in food,medicine,cosmetics and other fields in recent years for the reasons that it has strong ability of scavenging free radicals,anti-aging and the characters of natural,safe,non-toxic.As a natural and efficient antioxidant,ergothioneine plays an important role in the prevention and treatment of diseases related to oxidative stress.This paper reviewed the structure,properties and antioxidant properties,as well as progress in search of the role and mechanism of ergothioneine in the intervention of diseases related to oxidative stress,which provides a reference for the multiple application of ergothioneine.

Key words: ergothioneine, structure, antioxidant activity, oxidative stress, application

中图分类号:  R961 R965

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