天然产物研究与开发 ›› 2024, Vol. 36 ›› Issue (增刊1): 156-172.

• 综述 • 上一篇    下一篇

光皮木瓜的化学成分及药理活性研究进展

黄纪晟1,汪   琼2,徐增莱2,商国楚3,李   娜3,程志红1*   

  1. 1复旦大学药学院天然药物学系,上海 201203;2江苏省中国科学院植物研究所 江苏省植物资源研究与利用重点实验室,南京 210014;3陕西省白河县林业局,安康725899
  • 出版日期:2024-09-14 发布日期:2024-07-17

A review on chemical constituents and pharmacological activities of Chaenomeles sinensis

HUANG Ji-sheng1,WANG Qiong2,XU Zeng-lai2,SHANG Guo-chu3,LI Na3,CHENG Zhi-hong1*   

  1. 1Department of Natural Medicine,School of Pharmacy,Fudan University,Shanghai 201203,China;2Jiangsu Key Laboratory for the Research and Utilization of Plant Resources,Institute of Botany,Jiangsu Province & Chinese Academy of Sciences,Nanjing 210014,China;3Baihe County Forestry Bureau of Shaanxi Province,Ankang 725899,China
  • Online:2024-09-14 Published:2024-07-17

摘要:

光皮木瓜Chaenomeles sinensis (Thouin) Koehne为蔷薇科木瓜属植物。我国为光皮木瓜原产国,植物资源丰富,其果实在我国的一些地区如湖南、四川、山东等地作为地方习用药材被收入各地的地方中药材标准中。光皮木瓜经过国内外学者的大量研究,被发现其含有丰富的黄酮类、三萜类、木脂素类等化合物,具有抗氧化、抑菌消炎、抗肿瘤、抗老年痴呆、抗病毒等多种药理活性,具有很高的营养与药用价值。本文通过查阅国内外文献,对光皮木瓜的化学成分、药理及生物活性进行了综述,以期为光皮木瓜资源的深入开发和利用提供科学依据。

关键词: 光皮木瓜, 化学成分, 药理活性, 研究进展

Abstract:

Chaenomeles sinensis,a plant of Rosaceae Juss.,is indigenous to China and is abundant in natural resources.The fruit of this plant is used as a folk herbal medicine customarily used in certain regions in China such as Hunan,Sichuan,and Shandong provinces,and is recorded in their local standards for Chinese Materia Medica.This herb is reported to contain plenty of flavonoids,triterpenoids,and lignans,and possesses various activities such as anti-oxidative,anti-bacterial,anti-inflammatory,anti-tumor,anti-Alzheimer′s disease,and anti-viral activities.This paper focuses on the research advance of this herb on chemical constituents,pharmacological and biological activities through a systematic literature research,which facilitates the deep development and utilization of C. sinensis.

Key words: Chaenomeles sinensis, chemical constituents, pharmacological activities, research advance

中图分类号:  R932