关键词: 菊科, 地胆草, 化学成分, 结构鉴定

Abstract: To study the chemical constituents of Elephantopus scaber L.The isolation of ingredients was performed by chromatography on silica gel,Sephadex LH-20 and semi-preparative HPLC.Nine compounds were obtained from the 95% ethanol extract of E.scaber based on 1D,2D NMR,MS spectroscopic methods. Their structures were obtained and identified as 1-［(2R*,3S*)-3-ethoxy-2,3-dihydro-6-hydroxy-2-(1-methylethenyl)-1-benzofuran-5-yl］ethanone(1),7hydroxy-6-acetyl-2 methylchromone(2),matriisobenzofuran(3),betulinic acid(4),luteolin(5),luteolin-7-O-β-D-glucoside(6),p-coumaric acid(7),3,4-dihydroxy benzaldehyde(8)and stigmasterol-3-O-β-D-glucoside(9).Compounds 1-3 were isolated from the genus for the first time.The compound 3 was not reported from other plants in domestic.

Key words: Compositae, Elephantopus Scaber L., chemical constituents, structural identification