天然产物研究与开发 ›› 2017, Vol. 29 ›› Issue (2): 337-348.doi: 10.16333/j.1001-6880.2017.2.027

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类菌胞素氨基酸的结构特征、分布、制备技术及生物活性研究进展

王杰,张金荣*,严小军   

  1. 宁波大学海洋学院教育部应用海洋生物技术重点实验室,宁波 315211
  • 出版日期:2017-02-28 发布日期:2017-03-07

Review on Chemical Structure,Distribution,Preparation Technology,Biological Activity of Mycosporine-like Amino Acids

WANG Jie,ZHANG Jin-rong*,YAN Xiao-jun   

  1. Key Laboratory of Applied Marine Biotechnology,Ministry of Education,School of Marine Sciences,Ningbo University,Ningbo 315211,China
  • Online:2017-02-28 Published:2017-03-07

摘要: 类菌胞素氨基酸(mycosporinelike amino acids,MAAs)是一类水生生物次级代谢产物,广泛存在于多种水生生物中。在化学结构上,MAAs是以环己烯酮为基本骨架,与多种类型氨基酸通过缩合作用而形成水溶性活性物质。据报道,类菌胞素氨基酸具有罕见的紫外光防护作用,近年来已倍受重视,成为研究热点。本文主要介绍类菌胞素氨基酸的结构、分布、制备技术、生物活性及其在化妆品领域应用的研究进展。

关键词: 类菌胞素氨基酸, 紫外线防护, 分布, 制备技术, 生物活性

Abstract: Mycosporine-like amino acids (MAAs) are a class of secondary metabolites of aquatic organisms and widely found in many kinds of aquatic organisms.In the chemical structure,they are water-soluble active substances formed through condensation of cyclohexenone,the basic skeleton,with a variety of amino acids.According to reports,MAAs exhibited rare photoprotective effect.In recent years,they have been taken more and more attention and have becoming a research focus.This paper mainly introduced the research on the chemical structure,distribution,preparative technique and bioactivities of MAAs and their application in cosmetics.

Key words: mycosporine-like amino acids, UV-protective, distribution, preparation, biological activity

中图分类号: 

R282.77