关键词: 大蒜素, 大负荷运动, 恢复期, 氧化应激, 总抗氧化能力

Abstract: This study aimed to probe the effects of allicin preconditioning on plasma antioxidative capacity of rats immediately after exercise as well as in 12 hours and 24 hours after higher loading exercise,and accordingly to analyze the mechanism.Sixty-four male adult SD rats were randomly divided into two groups:placebo group (Group C) and allicin group (Group D).Rats in Group D were fed with allicin on gavage administration and the timing dosage was 30 mg/kg/d.Rats in Group C were fed with placebo (distilled water),whose dosage was the same as that in group D.After two weeks,the contents of plasma glutathione (GSH),glutathione peroxidase (GSH-Px),superoxide dismutase (SOD),malondialdehyde (MDA) and the levels of total antioxidative capacity (TAC) were measured in both groups before and immediately after exercise as well as in 12 hours and 24 hours after higher loading exercise.The results showed that the GSH-Px of Group D was significantly increased (P<0.01) compared with that of Group C;the GSH and SOD of Group D were increased (P<0.05) immediately after exercise and in 12 hours after exercise;TAC of Group D was also significantly increased immediately after exercise as well as in 12 hours and 24 hours after exercise;whereas the change of MDA was opposite to SOD.The results indicated that allicin preconditioning was helpful for improving plasma antioxidative capacity in rats after higher loading exercise.

Key words: allicin, heavy load exercise, during recovery period, antioxidation, total antioxidant capacity