天然产物研究与开发 ›› 2016, Vol. 28 ›› Issue (11): 1845-1849.doi: 10.16333/j.1001-6880.2016.11.028

• 综述 • 上一篇    下一篇

辣木的抗肿瘤活性及作用机制研究进展

曹玉霖,何镇廷,朱彦锋*   

  1. 成都医学院公共卫生系,成都 610500
  • 出版日期:2016-11-30 发布日期:2017-03-30

Review on Anti-tumor Effect and Potential Mechanisms of Moringa oleifera Lam

CAO Yu-lin,HE Zhen-ting,ZHU Yan-feng*   

  1. Department of Public Health,Chengdu Medical College,Chengdu 610500,China
  • Online:2016-11-30 Published:2017-03-30

摘要: 辣木,原产于印度,被用作日常蔬菜和食品,被认为有食疗保健的功效。研究发现辣木具有降血糖、治疗溃疡、消炎抑菌、降低血压和胆固醇、改善凝血等功效,被广泛应用于医药、保健等方面。近年来发现,其在抗肿瘤方面亦有显著效果。目前,辣木的抗肿瘤作用已成为研究的热点,研究发现其对多种肿瘤均有抑制作用,作用机制包括抑制癌细胞的生长增殖、调节癌细胞周期、诱导癌细胞凋亡、干扰癌细胞信号通路、抗氧化损伤,降低活性氧水平、抑制蛋白合成等。本文就近年来国内外的辣木抗肿瘤效应的相关研究作一综述。

关键词: 辣木, 抗癌, 机制

Abstract: Moringa oleifera,originating in India,has been used as vegetables and foods to enhance the functions of nutrition and therapeutic care. M.oleifera has shown various functions,such as decreasing blood glucose,treating ulcer,anti-inflammatory,antibacterial,reducing blood pressure,lowering cholesterol.In recent years,studies found that M.oleifera has certain anti-tumor effects.The proposed mechanisms include inhibiting cancer cell proliferation,regulating cancer cell period,inducing apoptosis,interfering signaling pathways,anti-oxidation,inhibiting protein synthesis,etc.In this study,the anti-tumor effect of M.oleifera as well as its potential mechanisms were summarized.

Key words: Moringa oleifera, anti-tumor, mechanisms

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