关键词: 马兜铃属, 长叶马兜铃, 化学成分

Abstract: Chemical investigation of roots of Aristolochia championii lead to the isolation of sixteen compounds by various chromatographies such as silica gel,Sephadex LH20,and RPC18 column chromatography.Their structures were determined to be:debilon (1),1αhydroxy9aristolen8one (2),(4S)4hydroxyl1,10secomuurol5ene1,10dione (3),homalomenol (4),cyclo(LLeuLPro) (5),lasiodiplodin (6),oxyphyllenodiol A (7),(7R,9R,10R)3,9dihydroxycalameneno (8),1β,11dihydroxy5eudesmene (9),vomifoliol (10),threo2,3bis(4hydroxy3methoxyphenyl)3ethoxypropan1ol (11),pollenfuran A (12),Ntranssinapoyltyramine (13),Ntransferuloyltyramine (14),1,2dihydro6,8dimethoxy7hydroxy1(3,5dimethoxy4hydroxyphenyl)N1,N2bis［2(4hydroxyphenyl)ethyl］2,3naphthalene dicarboxamide (15),grossamide (16),respectively,based on the spectral analysis such as NMR,MS,etc.Compounds 116 were isolated from this plant for the first time.Compounds 39,11,12,15 and 16 were obtained from this genus for the first time.

Key words: Aristolochia, Aristolochia championii, chemical constituents