关键词: 寻甸, 臭参, 木脂素, 黄酮

Abstract: Twenty four compounds were isolated from the roots of Codonopsis pilosula produced in Xundian of Yunnan province,which is well known as Choushen.Their structures were identified as choushenglycolipid A (1),(-)-(7R,8S,7′E)-4-hydroxy-3,5′-dimethoxy-7,4′-epoxy-8,3′-neolign-7′-ene-9,9′-diol 9′-ethyl ether (2),(7S,8R)-dihydrodehydrodiconiferyl alcohol (3),3-O-demethyldihydrodehydrodiconiferyl alcohol (4),prunustosanan AI (5),threo-guaiacylglycerol-β-O-4-lariciresinol ether (6),(+)-lariciresinol (7),5′-methoxylariciresinol (8),(-)-(7′S,8S,8′R)-4,4′-dihydroxy-3,3′,5,5′-tetramethoxy-7′,9-epoxy-lignan-9′-ol-7-one (9),(7S,8S)-3-methoxy-3′,7-epoxy-8,4′-oxyneoligna-4,9-diol 9′-O-β-D-glucopyranoside (10),(-)-secoisolariciresinol (11),(+)-isolariciresinol (12),burselignan (13),threo-guaiacylglycerol-β-O-4′-coniferyl ether (14),4-［1-ethoxyl-1-(4-hydroxy-3-methoxy)benzyl］methyl-2-(4-hydroxy-3-methoxy)benzyl-3-hydroxymethyl-tetrahydro-furan (15),(-)-(7R,7′R,7′′R,8S,8′S,8′′S)-4′,4′′-dihydroxy-3,3′,3′′,5-tetramethoxy-7,9′:7′,9-diepoxy-4,8′′-oxy-8,8′-sesquineolignan-7′′,9′′-diol (16),(+)-pinoresinol-4′-O-β-D-glucopyranoside (17),retusin-8-methylether (18),ladanein (19),wighteone (erythrinin B) (20),3-methoxy-9-hydroxy-pterocarpan (21),trichocarpin (22),(Z)-8-O-β-D-glucopyranosylcinnamic acid (23) and 4-hydroxycinnamyl-O-β-D-glucopyranoside (24),respectively,by spectroscopic methods.Compound 1 is new and the other compounds with exception of compounds 7,11-13,23 and 24 were isolated from the genus Codonopsis for the first time.

Key words: Xundian, Codonopsis pilosula, lignans, flavones