关键词: 瑞香狼毒根部, 烷烃类提取物, 气相色谱-质谱法（GC-MS）, 正己烷, 抑瘤

Abstract: The components of the SRH which using hexane extracts the root of Stellera chamaejasme L.were analyzed by Gas Chromatography-Mass Spectrometry.Meanwhile,study the effects on H₂₂ cancer mice.The results indicated that 44 structures of the root of Stellera chamaejasme L.were identified by GC-MS analysis,these included 12 kinds of hydrocarbon compounds,10 kinds of aromatic compounds,9 kinds of acids compounds,7 kinds of esters compounds,4 kinds of alcohols compounds and 2 other types of compounds.The contents above 1% of the root of Stellera chamaejasme L.were (Z,Z)-9,12-octadecadienoic acid,di-2-ethylhexyl phthalate,9,17-octadecadienal,triacontahexaene,.gamma.-sitosterol,dibutyl phthalate,n-hexadecanoic acid,octadecanoic acid,eicosanoic acid,whose total peak area is 90.74%,detection of squalene,linoleic acid,campesteral have certain antitumor activity ani-tumor which has not been reported in Stellera chamaejasme L.The SRH was effective in inhibiting the growth of the tumor;especially the low dose of SRH,the inhibition rate reached 21.5%.The results provide a theoretical basis for the analysis ofmaterial composition and anti-tumor effects about the roots of Stellera chamaejasme L.

Key words: the root of Stellera chamaejasme L., SRH, gas chromatography-mass spectrometry (GC-MS), hexane, anti-tumor