天然产物研究与开发 ›› 2018, Vol. 30 ›› Issue (增刊1): 212-216.

• 综述 • 上一篇    下一篇

荞麦光敏素的提取分析与生物活性研究

芦莎,李艳琴*,李彬春   

  1. 山西大学生物技术研究所 化学生物学与分子工程教育部重点实验室,太原 030006
  • 出版日期:2018-07-31 发布日期:2018-07-31
  • 基金资助:

    山西省科技厅项目(201603D21108-4)

Advance on the Isolation,Analysis and Biological Activity of Fagopyrins

LU Sha, LI Yan-qin*, LI Bin-chun   

  1. Institute of Biotechnology of Shanxi University,Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education,Taiyuan 030006,China
  • Online:2018-07-31 Published:2018-07-31

摘要: 荞麦光敏素(Fagopyrins)是存在于荞麦植株中的一种具有光毒作用的苯丙二蒽酮物质,动物或人食用过多会产生荞麦光敏症(Fagopyrism),例如:皮炎,脱发,气喘,昏厥等。同时,荞麦光敏素还具有抗菌、抗病毒和抗肿瘤等广泛的生物和药理活性,并可用于光动力治疗。我国作为荞麦生产和消费大国,对荞麦光敏素的研究鲜有报道。本文根据近年来国外对荞麦光敏素的研究,在其化学结构、提取、分析及生物活性等方面进行综述,以期为荞麦光敏素的进一步研究提供参考。

关键词: 荞麦光敏素, 化学结构, 提取, 分析, 生物活性

Abstract: Fagopyrins was a group of naphthodianthrone found in buckwheat.Because of its phototoxicity,Fagopyrins could cause fagopyrism when overly consumed by humans and animals.Syndromes included skin inflammation,hair loss,asthma and fainting.In the meanwhile,Fagopyrins also had a wide range of biological and pharmacological activities,such as antibacterial,antivirus and antitumor activities,which enable them to be used in photodanamic therapy.As a great country of buckwheat production and consumption,the research on the photosensitive element of buckwheat was however poorly documented.In this paper,such researches were reviewed.The chemical structure,extraction,analysis and bioactivity study of Fagopyrins were discussed,providing reference for further study.

Key words: Fagopyrins, chemical structure, extraction, analysis, biological activities

中图分类号:  Q946