天然产物研究与开发 ›› 2019, Vol. 31 ›› Issue (1): 175-183.doi: 10.16333/j.1001-6880.2019.1.027

• 综述 • 上一篇    

奶子藤属植物中生物碱研究进展

王亚兰1,2,3,王晓静1,2,4*,王志伟3*   

  1. 1济南大学 山东省医学科学院医学与生命科学学院,济南 250200;2山东省医学科学院药物研究所,济南 250062;3山东省分析测试中心 齐鲁工业大学(山东省科学院),济南 250014;4国家卫生部生物技术药物重点实验室 山东省罕少见病重点实验室,济南 250062
  • 出版日期:2019-01-28 发布日期:2019-01-28
  • 基金资助:

    国家自然科学基金(31700290);山东省医学科学院医药卫生科技创新工程

Research progress on alkaloids of genus Bousigonia

WANG Ya-lan1,2,3, WANG Xiao-jing1,2,4*, WANG Zhi-wei3*   

  1. 1School of Medicine and Life Sciences,University of Jinan-Shandong Academy of Medical Sciences,Jinan 250200,China; 2Institute of Materia Medica,Shandong Academy of Medical Sciences,Jinan 250062,China; 3Shandong Analysis and Test Center,Qilu University of Technology (Shandong Academy of Sciences),Jinan 250014,China; 4Key Laboratory for Biotech-Drugs Ministry of Health,Key Laboratory for Rare-Uncommon Diseases of Shandong Province,Jinan 250062,China
  • Online:2019-01-28 Published:2019-01-28

摘要: 奶子藤属植物为傣族传统常用药材,含有大量结构复杂,生物活性良好的生物碱类成分。本文针对奶子藤属植物中已分离鉴定的95个生物碱及其体外抗肿瘤和抗HIV活性研究进行了系统综述,为更加合理地开发利用奶子藤属植物资源提供参考依据。

关键词: 奶子藤属, 奶子藤, 闷奶果, 生物碱, 研究进展

Abstract: The genus Bousigonia was a well-known traditional medicine of Dai nationality,which contained a lot of alkaloids with complex and variable structures and good biological activities.In this paper,the research on the structure types and anti-tumor and anti-HIV activities in vitro of 95 alkaloids isolated from genus Bousigonia were systematically reviewed,which would provide a reference for more reasonable development and utilization the plant resources of the genus Bousigonia in the follow-up study.

Key words: genus Bousigonia, Bousigonia mekongensis Pierre, Bousigonia angustifolia Pierre, alkaloids, review

中图分类号: 

R931.71 Q946