天然产物研究与开发 ›› 2019, Vol. 31 ›› Issue (9): 1552-1558.doi: 10.16333/j.1001-6880.2019.9.010

• 研究简报 • 上一篇    下一篇

竹叶花椒枝和叶精油化学成分及其对二磷酸腺苷诱导血小板聚集的影响研究

马 捷1,2，李 梅1*，宁莉萍1*，王景燕1,3，龚 伟1,3，高 玥1，丁 文1，唐 诗1   

  1. 1四川农业大学林学院，成都611130；2四川旅游学院，成都610100；3四川农业大学生态林业工程省级重点实验室，成都611130
  • 出版日期:2019-10-09 发布日期:2019-10-23
  • 基金资助:

    “十二五”国家科技支撑计划(2011BAC09B05)；四川省科技计划（2018JY0494）；四川省农业科技成果转化项目（16NZ0067）；四川省教育厅自然科学一般项目（18ZB0445）

Chemical constituents of essential oils from branches and leaves of Zanthoxylum armatum DC.and their effects on adenosine diphosphate induced platelet aggregation


MA Jie1,2,LI Mei1*,NING Li-ping1*,WANG Jing-yan1,3,GONG Wei1,3,GAO Yue1,DING Wen1,TANG Shi1   

  1. 1 Forestry of college,Sichuan Agricultural University,Chengdu 611130,China; 2 Sichuan Tourism University,Chengdu 610100,China; 3Sichuan Provincial Key Laboratory of Ecological Forestry Engineering,Sichuan Agricultural University,Chengdu 611130,China
  • Online:2019-10-09 Published:2019-10-23

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摘要： 为高效利用竹叶花椒（Zanthoxylum armatum DC.）废弃资源，本研究采用水蒸气蒸馏法提取竹叶花椒枝和叶精油，通过气相色谱质谱联用仪测定其化学成分，发现竹叶花椒叶精油的提取量大于枝精油；枝精油主要化学成分为2-十三酮19.09%，9-十八烯醛11.57%，叶精油为芳樟醇62.01%，2-十一酮9.83%。两种精油主要化学成分相似度较高，16种共同共有化学成分分别占总量的52.51%和87.6%。经血小板聚集仪研究精油抗二磷酸腺苷诱导的血小板聚集活性，发现叶精油能显著抑制血小板聚集，抑制率为67.4% ± 24%。因此，生产实践中可考虑混合提取竹叶花椒枝和叶精油，开发为香料、香精及药品的低成本原料。

关键词: 竹叶花椒, 精油, 化学成分, 血小板聚集

Abstract: In order to provide references for the efficient utilization of Zanthoxylum armatum DC.waste resources,the essential oils from the branches and leaves of Zanthoxylum armatum DC.were extracted by steam distillation.The chemical constituents were determined by gas chromatography-mass spectrometry.It was found that the extraction amount of essential oils from the leaves of Zanthoxylum armatum DC.was greater than that from the branches.The main chemical constituents of branch oils were 2-Tridecanone 19.09%,9-Octadecenal-11.57%,and that of leave oils were Linalool 62.01%,2-Undecanone 9.83%.The main chemical constituents of the two essential oils had high similarity,and the 16 common chemical constituents account for 52.51% and 87.6% of the total respectively.The antiplatelet aggregation activity of essential oil against adenosine diphosphate-induced platelet aggregation was studied by platelet aggregation analyzer.It was found that leave oils could significantly inhibit platelet aggregation with an inhibition rate of 67.4% ± 24%.Therefore,in the production practice,the essential oil can be extracted from the branches and leaves of Zanthoxylum armatum DC.by mixing them.Essential oils can be developed as low cost raw materials for spices,flavors and pharmaceuticals.

Key words: Zanthoxylum armatum DC., essential oil, chemical composition, platelet aggregation

中图分类号: 

R284.2 R961

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