天然产物研究与开发 ›› 2020, Vol. 32 ›› Issue (增刊2): 164-171.

• 综述 • 上一篇    下一篇

岭南药材牛大力化学成分及药理研究进展

刘蕊1,2,张景照1,2,赵欣1,2,周艳丽3,4,金红5*,唐旭东1,2*


  

  1. 1深圳清华大学研究院创新中药及天然药物研究重点实验室,;2广东省创新中药及天然药物研究工程中心;3深圳松乐生物科技有限公司,深圳 518057;4广东霖善堂生物科技有限公司,河源 517000;5深圳市中国科学院仙湖植物园,深圳 518057

  • 出版日期:2020-12-09 发布日期:2020-12-09
  • 基金资助:
    深圳市出站博士后科研资助(2019年第一批);深圳市科技计划(JCYJ20160510141910129)

Chemical constituents and biological activities of Millettia specisoa Champ.

LIU Rui1,2,ZHANG Jing-zhao1,2,ZHAO Xin1,2,ZHOU Yan-li3,4,JIN Hong5*,TANG Xu-dong1,2*#br#

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  1. 1Key Lab for New Drugs Research of TCM in Shenzhen,Research Institute of Tsinghua University in Shenzhen;2Guangdong Innovative Engineering Research Center of Traditional Chinese Medicine and Natural Medicine,Research Institute of Tsinghua University in Shenzhen;3Shenzhen Songle Biotechnology Co.,Ltd.,Shenzhen 518057,China;4GD Linshantang Biotechnology Co.,Ltd.,Heyuan 517000,China;5Fairy Lake Botanical Garden,Shenzhen Chinese Academy of Sciences,Shenzhen 518057,China

  • Online:2020-12-09 Published:2020-12-09

摘要: 岭南药材牛大力在我国南方地区常被用来煲汤,制备药膳和药酒,具有补腰肾、强筋骨等功效。临床中成药如壮腰健肾丸、强力健身胶囊和金鸡虎补丸等也含有牛大力药材。牛大力的主要化学成分包括三萜类、黄酮类、酚类、木脂素类、生物碱类和多糖类等。现代药理实验表明,牛大力具有抗氧化、抗炎、抗疲劳和调节免疫力等作用。本文对牛大力的化学成分和药理活性进行综述,为牛大力的深入研究和牛大力产品开发提供了科学理论依据。


关键词: 岭南药材牛大力, 化学成分, 药理活性, 产品开发

Abstract:

Millettia specisoa Champ.is usually used to stew soup,and prepare medicinal dishes and medicinal liquor in southern China.It owns the effects of tonifying the waist and kidney,and strengthening the muscles and bones.Clinical Chinese patent medicine,such as Zhuangyao Jianshen Pills,Qiangli Jianshen Capsules,and Jinji Hubu Pills,also contain M. specisoa.The main chemical components of  M. specisoa include triterpenoids,flavonoids,phenols,lignans and alkaloids.Modern pharmacological experiments show that  M. specisoa has a variety of bioactivities such as anti-oxidation,anti-inflammatory,and anti-fatigue and immunomodulation.In the present article,the chemical components and pharmacological activities of  M. specisoa are reviewed,which provides a scientific theoretical basis for further study and product development of  M. specisoa.

Key words: Millettia specisoa Champ.;chemical constituents;biological activities, product development

中图分类号:  R961