The flavonoid myricetin (MYR) has antitumor,antioxidant and other pharmacological effects,but its role in immune regulation is not fully understood.Therefore,the effect of MYR on immune function was investigated by establishing a immune mouse model of cyclophosphamide (CTX).The relief degree of symptoms of myricetin was evaluated by weighing spleen and thymus and calculation index.The proliferation of T and B lymphocytes,the distribution of T cell subpopulations,the content of serum hemolysin,the number of antibody forming cells and the secretion levels of cytokines interleukin-2,interleukin-4,interleukin-6,interferon-γ were detected by MTT assay,hemolysis test,enzyme-linked immunosorbent assay and other immunological techniques.Experimental data show that myrictin can improve the mouse immune organ spleen,thymus index,promote the secretion of T lymphocytes and B lymphocyte cells,improve the level of cytokines and antibody forming cells.The results show that myrictin plays a positive role in the immune response,regulate the interaction between immune cells and cytokines to restore the balance of immunity,improve the symptoms of low immunity.