天然产物研究与开发 ›› 2023, Vol. 35 ›› Issue (增刊2): 72-75.

• 研究简报 • 上一篇    下一篇

唐古特铁线莲石油醚提取物的GC-MS分析

陈静华1,2,3,吴小可1,2,3,祁萍喜1,于瑞涛1,3*   

  1. 1中国科学院西北高原生物研究所 青海省藏药研究重点实验室,西宁 810008;2中国科学院大学,北京 100049;3中国科学院藏药研究重点实验室,西宁 810008
  • 出版日期:2023-12-27 发布日期:2023-12-11
  • 基金资助:
    青海省科技项目(2021-HZ-806);青海省自然基金面上项目(2022-ZJ-930);青海省藏药研究重点实验室创新平台发展建设专项(2022-ZJ-Y03)

GC-MS analysis on petroleum ether extract of Clematis tangutica (Maxim.) Korsh.

CHEN Jing-hua1,2,3,WU Xiao-ke1,2,3,QI Ping-xi1,YU Rui-tao1,3*   

  1. 1 Qinghai Provincial Key Laboratory of Tibetan Medicine Research,Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining 810008,China; 2 University of Chinese Academy of Sciences,Beijing 100049,China;3Key Laboratory of Tibetan Medicine Research,Chinese Academy of Sciences,Xining 810008,China
  • Online:2023-12-27 Published:2023-12-11

摘要:

唐古特铁线莲作为青藏高原常见的铁线莲属植物,是藏药“叶濛”的原植物之一。为研究其不同部位的药用价值,本文对采集自青海省的唐古特铁线莲样品进行了化学成分分析。样品经过乙醇浸提、石油醚萃取后上硅胶柱用石油醚-乙酸乙酯溶剂体系洗脱,对其中石油醚洗脱的馏分浓缩后进行GC-MS分析,共分析出17种化合物,其中含量最高为二十九烷(32.02%)和4-甲基辛烷(13.88%),烷烃类占99.01%,其余还有角鲨烯等化合物,未发现其含有甾醇类物质。实验结果表明,唐古特铁线莲石油醚部位的化合物种类较为单调,利用价值较低。本文对较少受到关注的唐古特铁线莲石油醚部位进行了研究,为全面分析其各部位成分构成提供参考。

关键词: 气相色谱-质谱联用, 唐古特铁线莲, 石油醚提取物, 植物甾醇

Abstract:

Clematis tangutica,a common Clematis on the Qinghai-Tibet Plateau,is one of the original plants of Tibetan medicine "Dbyi-mong".To study the medicinal value of its different parts,the chemical constituents of C. tangutica collected in Qinghai Province were analyzed.The extract of C.tangutica was isolated by silica gel column chromatography.The petroleum ether fraction was concentrated and analyzed by GC-MS.A total of 17 components were detected,of which the highest content was nonacosane(32.02%) and 4-methyloctane(13.88%),and alkanes accounted for 99.01%.Other compounds such as squalene were also analyzed,and no phytosterols were found.The results show that the compounds in the petroleum ether fraction of C. tangutica are relatively monotonous and the utilization value is low.This paper studies the petroleum ether part of C. tangutica that has received less attention,and provides a basis for the further comprehensive study of its chemical constituents.

Key words: GC-MS, Clematis tangutica, petroleum ether extract, phytosterols

中图分类号:  R284.2