三萜酚酸酯类化合物的研究进展

天然产物研究与开发 ›› 2011, Vol. 23 ›› Issue (2): 369-373.

三萜酚酸酯类化合物的研究进展

孙梦颖^1,2，梁敬钰^1*，冯煦²，董云发²，印敏²，陈雨²

¹中国药科大学天然药物化学教研室，南京 211198；²江苏省中国科学院植物研究所江苏省药用植物研究开发中心，南京 210014

收稿日期:2009-09-01 出版日期:2011-04-25 发布日期:2011-10-14
通讯作者: fengxu@mail.cnbg.net
基金资助:
江苏省科研条件与设备专项（2006507）

Research Progress on Triterpene Phenolic Acid Esters

SUN Ming-ying^1,2 , LIANG Jing-yu^1* , FENG Xu², DONG Yun-fa², YIN Min², CHEN Yu²

¹Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing211198, China; ²Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Jiangsu center for Research & Development of Medicinal Plants, Nanjing 210014, China

Received:2009-09-01 Online:2011-04-25 Published:2011-10-14

摘要/Abstract

摘要：

三萜酚酸酯类化合物是一类结构新颖的天然产物，本文从植物来源、结构类型及生物活性等方面综述了三萜酚酸酯类化合物的研究进展。

关键词: 三萜酚酸酯, 来源, 结构类型, 生物活性

Abstract:

Triterpenoid acid esters are a class of novel natural products. In this review，the progress in the research of the triterpene phenolic acid esters were reviewed with respect to the plant source，type of structure and biological activiies.

Key words: triterpene phenolic acid esters, plant source, structure type, biological activities

孙梦颖，梁敬钰，冯煦，董云发，印敏，陈雨. 三萜酚酸酯类化合物的研究进展[J]. 天然产物研究与开发, 2011, 23(2): 369-373.

SUN Meng-Ying, LIANG Jing-Yu, FENG Xu, DONG Yun-Fa, YIN Min, CHEN Yu. Research Progress on Triterpene Phenolic Acid Esters[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2011, 23(2): 369-373.

参考文献

1 Inubushi Y,et al.Phlegmanol A,dihydrocaffeic acid ester of the triterpene serratenediol.J Chem Soc D,Chem Commun,1970,17:1118-1119.
2 Shi H,et al.A new serratane-type triterpene from Lycopodium phlegmaria.Nat Prod Res,2005,19:777-781.
3 Zhou H,et al.Serratene-type triterpenoidsfrom Huperzia serrata.J Nat Prod,2003,66:1328 -1332.
4 Fuchino H,et al.Chemical evaluation of Betula species in Japan.III.Constituents of Betula maximowicziana.Chem Pharm Bull,1996,44:1748-1753.
5 Caballero P,et al.The isolation and molecular structure of lupeol -phenylpropionate from Cnidosculos elasticus.J Nat Prod,1984,47:819-821.
6 Maes L,et al.Comparative activities of the triterpene saponin maesabalide III and liposomal amphotericin B (AmBisome) against Leishmania donovani in hamsters.Antimicrob Agents Chemother,2004,48:2056-2060.
7 Maes L,et al.In vitro and in vivo activities of a triterpenoid saponin extract (PX-6518) from the plant Maesa balansae against visceral Leishmania species.Antimicrob Agents Chemother,2004,48:130-136.
8 Wood CA,et al.A bioactive spirolactone iridoid and triterpenoids from Himatanthus sucuuba.Chem Pharm Bull,2001,49:1477-1478.
9 Schuetz B,et al.Dammarane triterpenes from the leaves of Securinega melanthesoides.J Nat Prod,1998,61:96-98.
10 Li XC,et al.Antifungal jujubogenin saponins from Colubrina retusa.J Nat Prod,1999,62:674-677.
11 Takahashi H,et al.Coumaroyl triterpenes from Casuarina equisetifolia.Phytochemistry,1999 ,51:543-550.
12 Mulholland DA,et al.Glabretal triterpenoids from Dysoxylum muelleri.Phytochemistry,1996,42:1667-1671.
13 Majumder PJ,Pal Anjali.24-Methylene cycloartanyl p-hydroxycinnamate from the orchid Cirrhopetalum elatum.Phytochemistry,1985,24:2120-2122.
14 Pathak A,et al.Coumaroyl triterpene lactone,phenolic and naphthalene glycoside from stem bark of Diospyros angustifolia.Phytochemistry,2004,65:2153-2158.
15 Takahashi M,et al.In vitro leishmanicidal activity of some scarce natural products.Phytother Res,2004,18:573-578.
16 Majumder PL,et al.Structure of pholidotin,a new triterpene from orchids Pholidota rubra and Cirrhopetalum elatum.Phytother Res,2004,18:573-578.
17 Siddiqui S.,et al.Three pentacyclic triterpenoids from the leaves of Plumeria obtusa.J Nat Prod,1990,53:1332-1336. 18 Fuchino H,et al.Chemical evaluation of Betula species in Japan.I.Constituents of Betula ermanii.Chem Pharm Bull,1995,43:1937-1942.
19 Fuchino H,et al.Chemical evaluation of Betula species in Japan .II.Constituents of Betula platyphylla var.japonica.Chem Pharm Bull,1996 44:1033-1038.
20 Inubushi Y,et al.Triterpenoid constituents of Lycopodium phlegmaria L.J Chem SOC (C),1971,(18):3109-3114.
21 Masaiti Y,et al.Constituents of Lyonia ovalifolia var elliptica. XV. Constituents of the flowers. 2. Terpenoid constituents.3-O-p-hydroxy-trans-cinnamoylmaslinic acid and syntheses of related compounds.Yakugaku Zasshi,1971,91:1200-1206.
22 Siddiqui S,et al.Isolation and structure of neriucoumaric and isoneriucoumaric acids from the leaves of Nerium oleander.Planta Med,1987,53:424-427.
23 Yun BS,et al.Two bioactive pentacyclic triterpene esters from the root bark of Hibiscus syriacus.J Nat Prod,1999,62:764-766.
24 Lemos TLG De,et al.Terpenoids from Cnidoscolus phyllacanthus Pax et Hoff.J Brazil Chem Soc,1991,2:105-110.
25 Yan J,et al.Three new serratane triterpenoids from Phlegmariurus squarrosus.Helv Chim Acta,2006,89:2975-2980. 26 Orito K,et al.The triterpenes of Lycopodium lucidulum Michx.Can J Chem,1972,50:3280-3282.
27 Tong XT(童孝田),et al.Triterpenoid constituents of Huperzia miyoshiana.Chin J Chem,2003,21:1364-1368.
28 Chen B,et al.Triterpene caffeoyl ester and diterpene from Celastrus stephanotifolius.Phytochemistry,1999,51:683-687.
29 Tsutomu W,et al.Novel acylated saponins from Tragopogon porrifolius. Isolation and the structures of tragopogonsaponins A-R.Chem Pharm Bull,1991,39:388-396.
30 ElSohly HN, et al.New antimycobacterial saponin from Colubrina retusa.J Nat Prod,1999,62:1341-1342.
31 Flekhter OB,et al.Synthesis and antiinflammatory activity of new acylated betulin derivatives.Pharmaceut Chem J,2002,36:488-491.

[1]	陈家毅, 施冲煜, 石宣宜, 刘建群. 天然萜类木脂素化学结构及药理作用研究进展[J]. 天然产物研究与开发, 2024, 36(9): 1625-1637.
[2]	张梦娇, 邝天浩, 赵金诺, 朱婷, 彭娟娟. 华泽兰内生真菌Septoriella phragmitis次级代谢产物及其生物活性研究[J]. 天然产物研究与开发, 2024, 36(6): 986-992.
[3]	吴聪, 王文茂, 彭彩云, 盛文兵. 二氢杨梅素结构修饰及生物活性研究进展[J]. 天然产物研究与开发, 2024, 36(3): 540-553.
[4]	刘婷婷. 水飞蓟宾的植物来源、提取方法和抗癌活性研究进展[J]. 天然产物研究与开发, 2023, 35(增刊2): 154-163.
[5]	李彩霞, 多杰措, 宋文珠, 刘凤香, 马世震. 洋葱精油提取方法、化学成分及生物活性研究进展[J]. 天然产物研究与开发, 2023, 35(增刊1): 153-158.
[6]	俞静, 李宜航, 尹翠云, 邓招游, 唐德英, 张丽霞. 云南不同产地阳春砂内生真菌多样性分析及其活性研究[J]. 天然产物研究与开发, 2023, 35(9): 1540-1553.
[7]	谢博. 常见热加工方式对食源性活性成分影响的研究进展[J]. 天然产物研究与开发, 2023, 35(8): 1457-1467.
[8]	代梦媛, 高梅, 赵明辉, 李文昌. 蓖麻植物化学成分及生物活性研究进展[J]. 天然产物研究与开发, 2023, 35(7): 1265-1281.
[9]	刘猛, 章政, 高炳宏, 周志钦. 橘皮素生物活性及其对运动性哮喘的潜在功效[J]. 天然产物研究与开发, 2023, 35(6): 1088-1099.
[10]	代影, 杨帆, 林厚文. 极地放线菌次级代谢产物及药理活性研究进展[J]. 天然产物研究与开发, 2023, 35(5): 901-913.
[11]	田磊, 柳春燕, 韩军, 王国栋, . 黄精多糖结构特征及其生物活性研究进展[J]. 天然产物研究与开发, 2023, 35(3): 519-530.
[12]	伊丽, 孙茹欣, 何静, 明亮, 张秀荣, 吉日木图. 驼血蛋白中胰脂肪酶抑制肽的计算机模拟评估[J]. 天然产物研究与开发, 2023, 35(12): 2049-2060.
[13]	刘恃君, 陆玉爱, 李利, 汤杨黔南, 林丽美, 谢明霞, 夏伯候. 山银花油GC-MS及LC-MS的全成分表征及体外抗炎和抗氧化活性研究[J]. 天然产物研究与开发, 2023, 35(11): 1842-1856.
[14]	廖维, 宋娇, 韩丽, 张定堃. 天然产物色胺酮的研究进展[J]. 天然产物研究与开发, 2023, 35(11): 2003-2013.
[15]	童佳颖, 张鑫, 李娇, 张凤玲. Nigrospora属真菌化学成分及生物活性研究进展[J]. 天然产物研究与开发, 2022, 34(9): 1618-1631.