肉桂油纳米微乳的制备

天然产物研究与开发 ›› 2014, Vol. 26 ›› Issue (8): 1321-1326.

肉桂油纳米微乳的制备

章辉1,肖小年1,李莉2,易醒2*

1 南昌大学中德联合研究院；2 南昌大学中德食品工程中心,南昌 330047

出版日期:2014-08-30 发布日期:2014-11-06

Preparation of Cinnamon Oil Nanomicroemulsion

ZHANG Hui1, XIAO Xiao-nian1, LI Li2, YI Xing2*

1 Sino-German Joint Research Institute,Nanchang University;2Sino-German Food Engineering Center,Nanchang University,Jiangxi Nanchang 330047 ,China

Online:2014-08-30 Published:2014-11-06

摘要/Abstract

摘要： 本研究采用转相乳化法,结合伪三元相图制备肉桂油纳米微乳,对其外观、类型、理化性质、粒径及微观形态进行考察。最终得到肉桂油纳米微乳由EL-40/Tween80/无水乙醇/IPP/肉桂油/水组成,所制备的肉桂油微乳为O/W型微乳,淡黄色、澄清透明、流动性好,透射电镜下微乳颗粒大小均匀,平均粒径32 nm,电导率111.0 μs/cm,折光率1.415,黏度105 mpa.s,pH值5.24。

关键词: 转相乳化, 肉桂油, 纳米微乳, 伪三元相图

Abstract: In this study,phase inversion method,combined with pseudo-ternary phase diagram analysis was applied for the preparation of Cinnamon oil nanomicroemulsion(CONE).The appearance,types,physical and chemical properties,particle size and microstructure of CONE were explored.The final formulation was that the CONE was composed of EL-40/Tween 80/anhydrousethanol/IPP/cinnamon oil/water.The CONEwas O/W microemulsion withlight yellow color.It was clear transparent and had good liquidity.The particle size of microemulsion was uniform under the transmission electron microscope.The mean grain size,conductivity,refractive index,viscosity,pH value of CONE was determined to be 32 nm,111.0 μs/cm,1.415,105 mpa.s,and 5.24,respectively.

Key words: phase inversion method, cinnamon oil, nanomicroemulsion, pseudo-ternary phase diagram

中图分类号:

R283.6

章辉1,肖小年1,李莉2,易醒2*. 肉桂油纳米微乳的制备[J]. 天然产物研究与开发, 2014, 26(8): 1321-1326.

ZHANG Hui1, XIAO Xiao-nian1, LI Li2, YI Xing2*. Preparation of Cinnamon Oil Nanomicroemulsion[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2014, 26(8): 1321-1326.

[1]	王苗苗，李桂华，刘嘉琪，张蝶，何国威，刘建，唐伟卓*. 响应面优化回流提取桂花不同品种种子油工艺及脂肪酸组成分析[J]. 天然产物研究与开发, 2018, 30(11): 1986-1993.
[2]	刘莹1，杨海艳1，陈艳成1，杨姝慧1，林明霞1，王勇1,2*. 响应面法优化裸花紫珠叶中苯乙醇苷的醇提取工艺[J]. 天然产物研究与开发, 2018, 30(3): 495-500.
[3]	侯豹1，陈婷2，张治宣2，宫海凤2，杨薇2，蔡维维2，邱丽颖1,2*. 王不留行黄酮苷软膏剂体外透皮吸收研究[J]. 天然产物研究与开发, 2016, 28(12): 1978-1982.
[4]	王森1，欧水平2*，袁涛3 . 复方独一味凝胶贴膏的处方优化和制备工艺研究[J]. 天然产物研究与开发, 2016, 28(8): 1319-1324.
[5]	李思阳1，孔庆新1，张瑞2，王洋2*. 载10-甲氧基喜树碱缓释纳米粒的制备、表征与体外释药研究[J]. 天然产物研究与开发, 2016, 28(5): 724-727.
[6]	侯豹1，冯磊2，王旭2，刘艳玲1，蔡维维2，邱丽颖2*. 王不留行黄酮苷软膏剂的制备工艺研究[J]. 天然产物研究与开发, 2015, 27(11): 1853-1857.
[7]	赵鹏*，张婷婷. 响应面法优化金银花多糖羧甲基化工艺及抗氧化性研究[J]. 天然产物研究与开发, 2015, 27(1): 114-119.
[8]	赵鹏*，张婷婷，宋逍. 倒卵叶五加多糖的乙酰化工艺研究[J]. 天然产物研究与开发, 2014, 26(9): 1492-1496.
[9]	杨军宣1*，张海燕2，宋伟2，赵成城3，卢乾2，杨明2. 栀子环烯醚萜苷四种载药系统体外透膜吸收的比较研究[J]. 天然产物研究与开发, 2014, 26(6): 915-919.