低分子量卡拉胶马来酰化衍生物抗氧化性能研究

天然产物研究与开发 ›› 2014, Vol. 26 ›› Issue (6): 819-823.

低分子量卡拉胶马来酰化衍生物抗氧化性能研究

孙涛1,2*，王亚珍1，谢晶1，周冬香1，薛斌1

1 上海海洋大学食品学院；2 上海海洋大学海洋科学研究院，上海 201306

出版日期:2014-06-28 发布日期:2014-11-12

Antioxidant Activity of Low-Molecular-Weight κ-Carrageenans and Their Maleoyl Derivatives

SUN Tao1,2*, WANG Ya-zhen1, XIE Jing1, ZHOU Dong-xiang1, XUE Bin1

1 College of Food Science & Technology,Shanghai Ocean University;2 Institute of Marine Science,Shanghai Ocean University,Shanghai 201306 ,China

Online:2014-06-28 Published:2014-11-12

摘要/Abstract

摘要： 卡拉胶氧化降解制得两种卡拉胶低聚糖（A、B），进而与顺丁烯二酸酐反应合成得到两种低分子量卡拉胶马来酰化衍生物（MA、MB），对两种卡拉胶低聚糖及其衍生物的结构进行表征，分子量进行了测定。对四种物质进行了抗氧化性能的测定，包括超氧阴离子自由基、DPPH自由基的清除，以及还原能力的测定。上述物质抗氧化性能的能力为：MA > A，MB > B；B > A，MB > MA。实验结果说明，化学改性可以增强卡拉胶低聚糖的抗氧化活性，且分子量大，抗氧化活性好，这可能与卡拉胶分子的羟基数目以及取代基团的性质有关。

关键词: 低分子量卡拉胶, 马来酰化, 抗氧化性能

Abstract: Two low-molecular-weight (LMW) κ-carrageenans (A,B) were prepared by oxidative degradation of κ-carrageenan polysaccharides (KC).The LMW κ-carrageenans were then reacted with maleic anhydride to obtain two maleoyl LMW κ-carrageenans (MA,MB).Molecular weights and structural changes of A,B,MA and MB were determined.Their antioxidant activities were evaluated by superoxide anion radical (O₂^-·) scavenging assay,1,1-diphenyl-2-picrylhydrazyl radical (DPPH.) scavenging assay and total reducing power assay.The order of the antioxidant activities of the 4 investigated compounds was as follows:MA > A,MB > B;B > A,MB > MA.The results indicated that the chemical modification of LMW κ-carrageenans can enhance their antioxidant activity,and the antioxidant activity of LMW κ-carrageenans and their maleoyl derivatives increased with the increasing of molecular weights.These results were possibly related to the number of hydroxyl groups and the property of substituting groups.

Key words: Low-molecular-weight &kappa, -carrageenan, maleoyl, antioxidant activity

中图分类号:

R285 Q539 TS202.3

孙涛1,2*，王亚珍1，谢晶1，周冬香1，薛斌1. 低分子量卡拉胶马来酰化衍生物抗氧化性能研究[J]. 天然产物研究与开发, 2014, 26(6): 819-823.

SUN Tao1,2*, WANG Ya-zhen1, XIE Jing1, ZHOU Dong-xiang1, XUE Bin1. Antioxidant Activity of Low-Molecular-Weight κ-Carrageenans and Their Maleoyl Derivatives[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2014, 26(6): 819-823.

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