天然产物研究与开发 ›› 2014, Vol. 26 ›› Issue (4): 521-525.

• 研究简报 • 上一篇    下一篇

女贞树皮的化学成分研究

李启照*   

  1. 安徽新华学院药学院 安徽 230088
  • 出版日期:2014-04-30 发布日期:2014-11-19

Study on Chemical Constituents of the Ligustrum lucidum Bark

LI Qi-zhao*   

  1. Department of Pharmacology,Xin Hua College of Anhui,Hefei,230038,China
  • Online:2014-04-30 Published:2014-11-19

摘要: 采用硅胶、Sephadex LH-20等多种材料进行分离纯化,通过理化方法和波谱分析进行结构鉴定,从女贞树皮的醇提溶液的乙酸乙酯萃取部分中分离鉴定了19个化合物,分别为:尼克酰胺 (1);D-阿洛醇 (2);对羟基苯甲醇 (3);乙酰氧基齐墩果酸 (4);苯甲酸 (5);北升麻宁 (6);Borreriagenin (7);C-Veratroylglycol (8);methyl-2-O-β-glucopyranosylbenzoate (9);3′,7-二羟基-4′-甲氧基异黄酮 (10);7-羟基香豆素 (11);咖啡酸甲酯 (12);齐墩果酸 (13);(-)-襄五脂素 (14);莳萝油脑 (15);表儿茶素 (16);2α-羟基齐墩果酸 (17);桦木酸 (18);白桦脂醇 (19)。其中,化合物4、6、10、11、13、17、18、19已在女贞子中得到,但上述所有化合物均首次从女贞树皮中分离得到。

关键词: 女贞树皮, 提取, 分离, 结构鉴定

Abstract: 19 compounds were separated and purified from the ethyl acetate extracts in the alcohol solution of the Ligustrum lucidum bark silica gel and Sephadex LH-20 column chromatography.Their structures were identified as nicotinamide (1);D-allitol (2);p-hydroxybenzyl alcohol (3);Acetyloleanolic acid(4);benzoic acid (5);cimidahurinine (6);Borreriagenin (7);CVeratroylglycol (8);methyl-2-O-β-glucopyranosylbenzoate (9);3′,7-dihydroxy-4′-methoxyisoflavone(10);umbelliferone(11);caffeic acid methyl ester(12);oleanolic acid(13);(-)-chicanine(14);dillapiol(15);L-Epicatechin(16);2α-hydroxy-oleanolic acid (17);betulinic acid (18);Betulin(19),all the above compounds were isolated from the bark of Ligustrum lucidum for the first time,and compounds (4),(6),(10),(11),(13),(17),(18),(19) had been isolated from Ligustrum lucidum previously.

Key words: Ligustrum lucidum bark, extraction, isolation, structure identification

中图分类号: 

O629.9