天然产物研究与开发 ›› 2014, Vol. 26 ›› Issue (4): 626-631.

• 综述 • 上一篇    

n-6/n-3多不饱和脂肪酸比例对机体生理功能的调节

段叶辉1,2,李凤娜1*,李丽立1,印遇龙1   

  1. 1 中国科学院亚热带农业生态研究所 中国科学院亚热带农业生态过程重点实验室 湖南省畜禽健康养殖工程技术中心 农业部中南动物营养与饲料科学观测实验站,长沙 410125;2 中国农业科学院麻类研究所,长沙 410205
  • 出版日期:2014-04-30 发布日期:2014-11-19

The Regulation of n-6/n-3 Polyunsaturated Fatty Acid Ratio in Physiological Functions of the Body

DUAN Ye-hui1,2, LI Feng-na1*, LI Li-li1, YIN Yu-long1   

  1. 1 Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South Central,Ministry of Agriculture,Hunan Provincial Engineering Research Center for Healthy Breeding of Livestock and Poultry,Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha 410125China; 2 Institute of Bast Fiber Crops,Chinese Academy of Agricultural Sciences,Changsha 410205, China
  • Online:2014-04-30 Published:2014-11-19

摘要: 多不饱和脂肪酸(Polyunsaturated fatty acids,PUFA),尤其是n-6和n-3 PUFAs,不仅是人体必需营养素,在调节和预防人类疾病方面同时发挥着重要作用。n-6和n-3 PUFAs在哺乳动物细胞内不能相互转换,且是动植物细胞膜的重要组成成分,具有不同的生理功能。细胞膜多不饱和脂肪酸组成比例很大程度上由膳食决定,因此平衡膳食中n-6/n-3 PUFAs具有重要意义。本文总结了n-6和n-3 PUFAs的代谢途径和作用机制,结合临床试验,阐述了平衡n-6/n-3 PUFA的重要性。

关键词: PUFAs, n-6/n-3比例, 炎症, 调节

Abstract: Polyunsaturated fatty acids (PUFAs),especially n-6 and n-3 PUFAs,are not only the body's essential nutrients,but also play an important role in the regulation and prevention of human diseases.n-6 and n-3 PUFAs can not convert mutually in mammalian cells,having different physiological functions.The composition of polyunsaturated fatty acids in cell membranes is determined largely by diets,so balancing the ratio of n-6/n-3 PUFAs is very significant.This article summarizes the metabolic pathways and mechanisms of n-6 and n-3 PUFAs,and combines clinical trials,elaborating the importance of a balanced n-6/n-3 PUFAs ratio.

Key words: PUFAs, n-6/n-3 ratio, inflammation, regulation

中图分类号: 

O623.61