天然产物研究与开发 ›› 2014, Vol. 26 ›› Issue (Suppl2): 183-185.

• 研究论文 •    下一篇

红树植物桐花树内生真菌NAcFL10次生代谢产物的研究

鞠志冉1,2,王俊锋2,林秀萍2,田永奇2,刘芬1,徐石海1*,刘永宏2*   

  1. 1 暨南大学化学系,广州 510632;2 中国科学院南海海洋研究所 广东省海洋药物重点实验室,广州 510301
  • 出版日期:2014-12-30 发布日期:2015-03-05

Studies on Secondary Metabolites of an Endophytic Fungus NAcFL10 Obtained from Mangrove Plant Aegiceras corniculatum

JU Zhi-ran1,2, WANG Jun-feng2, LIN Xiu-ping2, TIAN Yong-qi2, LIU Fen1, XU Shi-hai1*, LIU Yong-hong2*   

  1. 1 Jinan University,Guangzhou,510632,China; 2 Guangdong Key Laboratory of Marine Materia Medica,South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou 510301,China
  • Online:2014-12-30 Published:2015-03-05

摘要: 对一株红树植物桐花树内生真菌NAcFL10的次生代谢产物进行研究,采用硅胶MPLC、Sephadex LH-20凝胶柱色谱、 常压硅胶柱色谱以及半制备高效液相色谱仪等手段从红树植物桐花树内生真菌NAcFL10的大米发酵物进行分离纯化得到7个化合物,并通过各种波谱数据、 文献对照分别鉴定为:leptosphaerin(1),二氢-4-羟基-5-羟甲基-2-呋喃酮(2),5-羟甲基糠醛(3),3,5,6-三甲基-2,4-二羟基-苯甲酸乙酯(4),胸苷(5),对羟基苯乙醇(6),麦角甾醇(7)。

关键词: 红树植物, 桐花树, 内生真菌, 次生代谢产物

Abstract: To study the secondary metabolites of an endophytic fungus NAcFL10,which was isolated from a mangrove plant Aegiceras corniculatum. Seven compounds were isolated from the fermentation of the fungus by using silica gel,Sephadex LH20,MPLC,and HPLC.The structures of the compounds were identified leptosphaerin(1),dihydro-4-hydroxy-5-hyroxymethyl-2-furanone(2),5-hydroxymethyl furaldehyde(3),2,4-dihydroxy-3,5,6-trimethylbenzoate(4),thymidine(5),tyrosol(6),and ergosterol(7)on the basis of spectroscopic analysis and comparison with reported data.

Key words: mangrove plant, Aegiceras corniculatum, endophytic fungus, secondary metabolites

中图分类号: 

R284.2