天然产物研究与开发 ›› 2015, Vol. 27 ›› Issue (10): 1693-1696.doi: 10.16333/j.1001-6880.2015.10.001

• 研究论文 •    下一篇

半夏中一个新的内酰胺化合物

高钦磊1,2,程永现1*   

  1. 1 中国科学院昆明植物研究所 植物化学与西部植物资源持续利用国家重点实验室,昆明 650201;2 中国科学院大学,北京 100049
  • 出版日期:2015-10-30 发布日期:2015-10-30

A New Lactam from Pinellia ternata

GAO Qin-lei1,2, CHENG Yong-xian1*   

  1. 1 State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201, China;  2 University of Chinese Academy of Sciences,Beijing 100049,China
  • Online:2015-10-30 Published:2015-10-30

摘要: 采用多种色谱技术从中药半夏中分离得到8个化合物,波谱学方法鉴定了它们的结构,分别为:半夏内酰胺(1)、2-(furan-2-yl)-5-(2,3,4-trihydroxy-butyl)-1,4-diazine(2)、环-(脯氨酸-亮氨酸)(3)、β-carboline(4)、芹菜素-6-C-阿拉伯糖-8-C-半乳糖苷(5)、芹菜素-6-C-半乳糖-8-C-阿拉伯糖(6)、6-O-angeloylprenolin(7)、4-O-methyl-3′-O-demethyl-secoisolariciresinol(8)。其中1是新化合物,2~8系首次从该药用部位中分离得到。

关键词: 半夏, 天南星科, 内酰胺

Abstract: Eight compounds were isolated from Pinellia ternate by utilizing various chromatographic methods. Their structures were identified as pinellactam (1),2(furan-2-yl)-5-(2,3,4-trihydroxy-butyl)-1,4-diazine (2),cyclo(Pro-Leu) (3),β-carboline (4),apigenin-6-C-arabinosyl-8-C-galactoside (5),apigenin-6-C-galactosyl-8-C-arabinoside (6), 6-O-angeloylprenolin (7) and 4-O-methyl-3′-O-demethyl-secoisolariciresinol (8),respectively,by spectroscopic data.Compound 1 is a new lactam and 2-8 were isolated from this material for the first time.

Key words: Pinellia ternata, Araceae, lactam

中图分类号: 

R284.2 Q946.91