关键词: 蛇莓, 提取物, 抗肿瘤

Abstract: In this study,we aimed on the extracts of Indian Mockstrawberry Herb.Organic solvents of various polarities (Petroleum ether,ethyl acetate and butanol) were used to extract the different components in the herb.The in vitro cytotoxicity of the extracts was evaluated by MTT assay to obtain a scientific basis for the further exploitation and application.IC₅₀ was used as evaluation criteria.The result showed that the extracts could significantly inhibited the growth of the cells of Hela,HepG2 and MCF-7. And as the polarity of organic solvents used reduced,the anti-tumor activity of the corresponding extract increased obviously.The sequence of anti-tumor activity,from strong to week,was petroleum ether section,ethyl acetate section and butanol section.And the sequence of the three solvents,also from strong to week,was butanol,ethyl acetate and ether.In conclusion,the component of Duchesnea indica herb with high polarity possesses a superior anti-tumor activity ageist tumor cells.

Key words: Indian Mockstrawberry Herb, extract, anti-tumor activity