NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2015, Vol. 27 ›› Issue (10): 1801-1810. doi: 10.16333/j.1001-6880.2015.10.021

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Correlation Analysis between Contents of Active Ingredients and Trace Elements in Hedysari Radix from Gansu Province

QIANG Zheng-ze, WANG Yan, LI Cheng-yi*, LI Shuo, WANG Ming-wei   

  1. Department of Pharmacy,Gansu College of Traditional Chinese Medicine,Lanzhou 730000,China
  • Online:2015-10-30 Published:2015-10-30

Abstract: This paper analyzed the correlation between contents of active ingredients and trace elements in Hedysari Radix,taking the Hedysari Radix cultivated in different regions of Gansu as the research objects.The content of 12 trace elements in Hedysari Radix were detected using flame atomic absorption spectrometry.The contents of calycosin and formononetin were determined by HPLC.Polysaccharide was determined by UV-Vis method.The correlations between contents of active ingredients and trace elements in Hedysari Radix were analyzed by correlation analysis and regression analysis.The result of correlation analysis showed that calycosin of Hedysari Radix had significant positive correlation with Fe,Mg contents;Formononetin had significant positive correlation with Fe,Ca,Ni,Mg contents and had a strong positive correlation with K content.However,it showed significant negative correlation with Cr,Li,Co contents;Polysaccharide had a negative correlation with Zn content and had significant negative correlation with Mg content.The contents of active ingredients of Hedysari Radix closely related with the trace elements,but the concrete quantitative relationship still need further study.

Key words: Hedysari Radix, trace elements, calycosin, formononetin, polysaccharide, correlation

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