NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2016, Vol. 28 ›› Issue (4): 486-489. doi: 10.16333/j.1001-6880.2016.4.003

• Article • Previous Articles     Next Articles

Cladosperanol A,a New Dimeric Tetralone from Marine-derived Fungus Cladosporium perangustum FS62

FAN Zhen1,2,3,SUN Zhang-hua2,CHEN Yu-chan2,LI Hao-hua2,ZHANG Wei-min2*   

  1. 1 South China Sea Insititute of Oceanology Chinese Academy of Sciences ,Guangzhou 510006,China; 2 State Key Laboratory of Applied Microbiology Southern China,Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application,Guangdong Open Laboratory of Applied Microbiology,Guangdong Institute of Microbiology,Guangzhou 510070,China; 3 University of Chinese Academy of Sciences,Beijing 100049,China
  • Online:2016-04-30 Published:2016-05-13

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Abstract: A new compound (1) was isolated from the fermentation broth extract of marine fungal strain Cladosporium perangustum FS62 by various chromatographic methods such as silica gel,reverse silica gel,Sephadex LH20,HPLC, etc. On the basis of detailed spectroscopic analysis (HR-ESI-MS,1D NMR,2D NMR,CD),1 was elucidated as a new dimeric tetralone with the structure of (4S,4′S)-4,8,8(trihydroxy-2,3,2′,3′- tetrahydro-［4′,5-binaphthalene］-1,1′(4H,4′H)-dione,named as cladosperanol A.

Key words: cladosperanol A, dimeric tetralone, secondary metabolite, Cladosporium perangustum, marine-derived fungus

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