Abstract: Seven compounds were isolated from the stem barks of Uncaria laevigata by repeated column chromatography over silica gel,MCI and RP18.On the basis of NMR and MS spectroscopic analysis,their structures were identified as roxburghine B (1),roxburghine C (2),roxburghine D (3),roxburghine X (4),Uncarine CN (4)oxide (5),(+)lyoniresinol 3αOβDglucoside (6),()lyoniresinol 3αOβDglucoside (7),respectively.Compound 5 was obtained from this genus for the first time and all the other compounds were isolated from this plant for the first time.

Key words: Uncaria laevigata, Uncaria, alkaloids, lignans, chemical constituents